Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level of activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells.
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Role of H-Ras/ERK signaling in carbon nanotube-induced neoplastic-like transformation of human mesothelial cellsRNA interference-directed knockdown of urokinase plasminogen activator and urokinase plasminogen activator receptor inhibits prostate cancer cell invasion, survival, and tumorigenicity in vivoUrokinase receptor and resistance to targeted anticancer agentsPlasminogen Activator System and Breast Cancer: Potential Role in Therapy Decision Making and Precision MedicineRegulation of Rac1 activation by the low density lipoprotein receptor-related proteinNeutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling.uPAR induces expression of transforming growth factor β and interleukin-4 in cancer cells to promote tumor-permissive conditioning of macrophages.uPAR induces epithelial-mesenchymal transition in hypoxic breast cancer cells.uPA is upregulated by high dose celecoxib in women at increased risk of developing breast cancer.Cleaved high-molecular-weight kininogen and its domain 5 inhibit migration and invasion of human prostate cancer cells through the epidermal growth factor receptor pathwayMasked Chimeric Antigen Receptor for Tumor-Specific Activation.Proteins and carbohydrates in nipple aspirate fluid predict the presence of atypia and cancer in women requiring diagnostic breast biopsy.Long-range signal transmission in autocrine relays.Serum-stable RNA aptamers to urokinase-type plasminogen activator blocking receptor binding.A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma.Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells.Overexpression of VEGF189 in breast cancer cells induces apoptosis via NRP1 under stress conditions.Regulation of alveolar epithelial cell apoptosis and pulmonary fibrosis by coordinate expression of components of the fibrinolytic systemDown-regulation of uPAR and uPA activates caspase-mediated apoptosis and inhibits the PI3K/AKT pathway.A transformation in the mechanism by which the urokinase receptor signals provides a selection advantage for estrogen receptor-expressing breast cancer cells in the absence of estrogenDesign, synthesis, biochemical studies, cellular characterization, and structure-based computational studies of small molecules targeting the urokinase receptor.Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation.Significance of the urokinase-type plasminogen activator and its receptor in the progression of focal segmental glomerulosclerosis in clinical and mouse models.RNAi-mediated downregulation of urokinase plasminogen activator receptor and matrix metalloprotease-9 in human breast cancer cells results in decreased tumor invasion, angiogenesis and growth.Sodium channel γENaC mediates IL-17 synergized high salt induced inflammatory stress in breast cancer cells.Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression functionThe inhibitory effect of HKa in endothelial cell tube formation is mediated by disrupting the uPA-uPAR complex and inhibiting its signaling and internalization.Gene expression profiling of circulating tumor cells and peripheral blood mononuclear cells from breast cancer patients.Amplification of the urokinase-type plasminogen activator receptor (uPAR) gene in ductal pancreatic carcinomas identifies a clinically high-risk group.Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell signaling.Key signalling nodes in mammary gland development and cancer. Mitogen-activated protein kinase signalling in experimental models of breast cancer progression and in mammary gland development.Cyr61 and YB-1 are novel interacting partners of uPAR and elevate the malignancy of triple-negative breast cancer.Targeting inflammatory pathways for tumor radiosensitization.The role of inflammatory pathways in cancer-associated cachexia and radiation resistance.Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy.Downregulation of urokinase plasminogen activator receptor expression inhibits Erk signalling with concomitant suppression of invasiveness due to loss of uPAR-beta1 integrin complex in colon cancer cells.uPAR peptide antagonist alters regulation of MAP kinases and Bcl-2 family members in favor of apoptosis in MDA-MB-231 cell lineStand-Sit Microchip for High-Throughput, Multiplexed Analysis of Single Cancer Cells.siRNA-mediated simultaneous downregulation of uPA and its receptor inhibits angiogenesis and invasiveness triggering apoptosis in breast cancer cells.Activators and inhibitors of the plasminogen system in Alzheimer's disease.
P2860
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P2860
Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level of activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Endogenously produced urokinas ...... DA-MB-231 breast cancer cells.
@ast
Endogenously produced urokinas ...... DA-MB-231 breast cancer cells.
@en
type
label
Endogenously produced urokinas ...... DA-MB-231 breast cancer cells.
@ast
Endogenously produced urokinas ...... DA-MB-231 breast cancer cells.
@en
prefLabel
Endogenously produced urokinas ...... DA-MB-231 breast cancer cells.
@ast
Endogenously produced urokinas ...... DA-MB-231 breast cancer cells.
@en
P2093
P1476
Endogenously produced urokinas ...... MDA-MB-231 breast cancer cells
@en
P2093
P304
P407
P577
2001-09-01T00:00:00Z