PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit. - Wikidata - awgldk - TriplyDB

PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit.

PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit.

http://www.wikidata.org/entity/Q30308560

about

Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway Copine-I represses NF-kappaB transcription by endoproteolysis of p65 Mechanisms of impaired differentiation in rhabdomyosarcoma To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis Regulation of NF-κB activation through a novel PI-3K-independent and PKA/Akt-dependent pathway in human umbilical vein endothelial cells RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling A transcriptomic computational analysis of mastic oil-treated Lewis lung carcinomas reveals molecular mechanisms targeting tumor cell growth and survival Piperlongumine inhibits NF-κB activity and attenuates aggressive growth characteristics of prostate cancer cells Chronic inflammation and cancer: potential chemoprevention through nuclear factor kappa B and p53 mutual antagonism A screen for transcription factor targets of glycogen synthase kinase-3 highlights an inverse correlation of NFκB and androgen receptor signaling in prostate cancer Down-regulation of PTEN by HCV core protein through activating nuclear factor-κB.CREB is a novel nuclear target of PTEN phosphatase.Suppression of PTEN expression by NF-kappa B prevents apoptosis.Expression of NF-κB and PTEN in primary epithelial ovarian carcinoma and the correlation with chemoresistance.PTEN enhances TNF-induced apoptosis through modulation of nuclear factor-kappaB signaling pathway in human glioma cells PTEN: a new guardian of the genome.Phosphatidylinositol 3-kinase interacts with the glucocorticoid receptor upon TLR2 activation.Akt-mediated regulation of NFkappaB and the essentialness of NFkappaB for the oncogenicity of PI3K and Akt The diverse and complex roles of NF-κB subunits in cancer.Gene expression profiling in conjunction with physiological rescues of IKKalpha-null cells with wild type or mutant IKKalpha reveals distinct classes of IKKalpha/NF-kappaB-dependent genes IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program.Somatostatin Derivate (smsDX) Attenuates the TAM-Stimulated Proliferation, Migration and Invasion of Prostate Cancer via NF-κB Regulation.Autocrine and paracrine promotion of cell survival and virus replication by human herpesvirus 8 chemokines.Hierarchical clustering of immunohistochemical analysis of the activated ErbB/PI3K/Akt/NF-kappaB signalling pathway and prognostic significance in prostate cancer.Phosphorylation of SIMPL modulates RelA-associated NF-kappaB-dependent transcription.The p38 mitogen-activated protein kinase regulates interleukin-1beta-induced IL-8 expression via an effect on the IL-8 promoter in intestinal epithelial cells.IKK beta and phosphatidylinositol 3-kinase/Akt participate in non-pathogenic Gram-negative enteric bacteria-induced RelA phosphorylation and NF-kappa B activation in both primary and intestinal epithelial cell lines.Combination of proteasomal inhibitors lactacystin and MG132 induced synergistic apoptosis in prostate cancer cells.Activation of nuclear factor-kappaB in human prostate carcinogenesis and association to biochemical relapse.NOX5 NAD(P)H oxidase regulates growth and apoptosis in DU 145 prostate cancer cells.Regulation of hypoxia inducible factor-1 by nitric oxide in contrast to hypoxia in microvascular endothelium.Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas.The flavonoid luteolin prevents lipopolysaccharide-induced NF-kappaB signalling and gene expression by blocking IkappaB kinase activity in intestinal epithelial cells and bone-marrow derived dendritic cells.Ultrafine carbon particles induce interleukin-8 gene transcription and p38 MAPK activation in normal human bronchial epithelial cells.Cucurbitacin B suppresses the transactivation activity of RelA/p65.PTEN reduces cuff-induced neointima formation and proinflammatory cytokines.

P2860

Q24306909-0A70F259-A352-48D3-BE8B-E7067D22CD4A Q24307551-E70AB930-403B-4D51-AD2D-2934D5C266FA Q26852728-0B62F89E-5B76-47B7-9F18-2464C7AF77CA Q28190313-A61A7B8F-75E6-4910-A4C1-0473178FD016 Q28484247-3CB48A8E-4DA8-4022-96D5-00A3F89855B0 Q33267561-DD9DC05E-DA9A-43E2-ABDE-F1DBF06A00F1 Q33518037-26079CF9-330E-4070-8935-14D049CA255F Q33738321-85B0827B-AF2F-4635-88C7-2EC3E7C681FB Q34079481-87B92475-0D54-496B-81FA-5F4067C2777E Q34483490-8C5B5D55-DBEB-4D06-BCDF-02744382877D Q34733201-3EDBBE08-EA81-48E6-B8B2-51868486C21A Q35019216-BDACB7B9-4ADE-47BB-BFB9-B58590930C0B Q35544303-2D965AA5-25EE-40F1-A4BD-DE69CAFAF507 Q36261565-83CDC7F4-E327-4A48-9187-7C9EA2DFE1A0 Q37243759-71025F3C-AB89-40BB-BA8E-BA81C214390F Q37270432-B28E14CD-A33A-4776-B091-194C1D58C532 Q37294519-CE80047A-BC0C-4E6C-B603-6DCD954F8530 Q37399825-211EA634-EE2E-49F8-9F9A-EC80B86CB203 Q37976939-9D42E462-EA0C-4C01-B645-6A613CE72D51 Q38330909-21D98E6B-3C95-4723-AD07-90B60841B579 Q38363101-B0B70949-200E-4FA4-92D3-F568A42A9C47 Q38870961-4EF42897-B643-4AF5-B85E-8FDDB0867DAE Q39767301-532DF6F1-DE4A-4569-A2B8-8930250A5BEA Q39986043-72DC3AEB-A300-459F-9510-9905980D5590 Q40213184-FBA96404-4D9A-4860-83D4-4324DA2018DA Q40660116-4EF1F1DF-CAE1-44BB-A519-7B22F0D49884 Q40715411-A1A218DE-406F-4A16-B929-DC1C8290E5B5 Q41472341-8F8DE986-015C-43E5-8EC7-2BC8D56E1E70 Q42022163-6A40E5FC-5006-4B6E-AEBE-2B49199A44E2 Q44397861-D682576F-1970-430C-9730-A9276404F77A Q44895310-8FE48FA9-B93B-4D6D-8331-2CC82CA0BF3D Q44927492-D892457C-987D-4E58-A184-C9B706CDDFA7 Q46536698-0F8DB31C-EA06-47F6-A936-1B499B32F45E Q47853105-345AC92E-63D9-4F06-9B31-10B2F9F5D0B2 Q54386411-5D365DDA-9D0B-4E67-BD1E-EEE867F7752B Q54447341-D3E43C3A-333C-4BA8-8507-708F5A8FA7DF

P2860

PTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit.

http://www.wikidata.org/entity/Q30308560

description

2002 nî lūn-bûn

@nan

2002 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

name

PTEN blocks tumor necrosis fac ...... potential of the p65 subunit.

@ast

PTEN blocks tumor necrosis fac ...... potential of the p65 subunit.

@en

type

label

PTEN blocks tumor necrosis fac ...... potential of the p65 subunit.

@ast

PTEN blocks tumor necrosis fac ...... potential of the p65 subunit.

@en

prefLabel

PTEN blocks tumor necrosis fac ...... potential of the p65 subunit.

@ast

PTEN blocks tumor necrosis fac ...... potential of the p65 subunit.

@en

P1433

Q30308560-C2523193-2E66-4794-AFC7-3DF8AC6A805A

P1476

Q30308560-53CBC0BE-E1CC-42BD-97C8-E68DFB7E359B

P2093

Q30308560-17CE8592-9A21-4D19-BF99-C2FCE1F29C6C

Q30308560-37AB5604-DBD8-4525-86BA-4751B8C61E10

Q30308560-41D8B224-D5CC-4BC0-BDA5-CD8EBE531601

Q30308560-5370FC7A-0A3C-4DF5-BCF5-0200E3033DAB

Q30308560-65F20B57-0AE5-41EA-8FF0-221DE4BF3B0F

Q30308560-660DED96-12F8-4018-B007-BCBA51071E30

Q30308560-AE0B5069-1B13-430F-B13B-D82BF4E2BBCF

P2860

Q30308560-0399D159-37DD-4D69-B757-1031487D230A

Q30308560-03BD7153-D27C-424A-945B-10268DBA73AE

Q30308560-068C8A32-E439-4D21-8FE0-80A118352B4D

Q30308560-083E5BF7-5715-4699-9507-E53D46710A4C

Q30308560-0BBDF609-1A58-4C0D-9185-AA79B59BA1A2

Q30308560-0C48CECA-750F-4480-BBD6-C11156A26D1D

Q30308560-11A5CBCC-5688-4B4B-B347-61AE7A377446

Q30308560-1D0FB6F7-041F-4D55-9C32-BF36A6CBFF25

Q30308560-30336C85-B387-4853-9E49-FD105112ADC6

Q30308560-35D1C46C-4033-427D-AE93-BFF88A54487A

P304

Q30308560-0CC906F5-6F92-4110-9CE9-88FF848C2FC7

P31

Q30308560-6DC9AF29-C44A-4543-B9EF-EC2DCA1126F1

P356

Q30308560-5ADFDCF4-45BB-49EC-B186-637A8C2A5E01

P407

Q30308560-CFDFADAA-34F9-427B-B4E5-1CF8E394E7BE

P433

Q30308560-ED126807-B2EB-4C8D-96F3-51603C5D3386

P478

Q30308560-A0294377-F964-4903-8865-D7DA9A5E611B

P577

Q30308560-A94F4565-46FA-4E37-836B-D0AFBD05CFFC

P698

Q30308560-B06C4B25-D699-4AFD-9970-D89AD8BACF51

P921

Q30308560-3117A75A-8263-43CC-8BE3-3F969127F859

P356

P1433

Journal of Biological Chemistry

P1476

PTEN blocks tumor necrosis fac ...... potential of the p65 subunit.

@en

P2093

Albert S Baldwin

http://www.w3.org/2001/XMLSchema#string

David R Jones

http://www.w3.org/2001/XMLSchema#string

Lee V Madrid

http://www.w3.org/2001/XMLSchema#string

Marty W Mayo

http://www.w3.org/2001/XMLSchema#string

Sandy D Westerheide

http://www.w3.org/2001/XMLSchema#string

Xiu-Juan Yuan

http://www.w3.org/2001/XMLSchema#string

Young E Whang

http://www.w3.org/2001/XMLSchema#string

P2860

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

NF-kappa B-inducible BCL-3 expression is an autoregulatory loop controlling nuclear p50/NF-kappa B1 residence

The NF-kappa B and I kappa B proteins: new discoveries and insights

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

NF-kappaB p105 is a target of IkappaB kinases and controls signal induction of Bcl-3-p50 complexes

Shared pathways of IkappaB kinase-induced SCF(betaTrCP)-mediated ubiquitination and degradation for the NF-kappaB precursor p105 and IkappaBalpha

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

P304

11116-11125

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M108670200

http://www.w3.org/2001/XMLSchema#string

P407

P433

13

http://www.w3.org/2001/XMLSchema#string

P478

277

http://www.w3.org/2001/XMLSchema#string

P577

2002-01-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

11799112

http://www.w3.org/2001/XMLSchema#string

P921