RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
about
Dephosphorylation of Carma1 by PP2A negatively regulates T-cell activationMapping a dynamic innate immunity protein interaction network regulating type I interferon productionPKC phosphorylation of TRAF2 mediates IKKalpha/beta recruitment and K63-linked polyubiquitinationTargeting protein serine/threonine phosphatases for drug developmentTNF biology, pathogenic mechanisms and emerging therapeutic strategiesStructural Basis for the Lack of E2 Interaction in the RING Domain of TRAF2Basic principles and emerging concepts in the redox control of transcription factorsSignaling network of dendritic cells in response to pathogens: a community-input supported knowledgebaseFrom sequence to function: using RNAi to elucidate mechanisms of human disease.Endosomal Nox2 facilitates redox-dependent induction of NF-kappaB by TNF-alpha.Oxidants positively or negatively regulate nuclear factor kappaB in a context-dependent mannerInterleukin-23 production in dendritic cells is negatively regulated by protein phosphatase 2APMC, a potent hydrophilic α-tocopherol derivative, inhibits NF-κB activation via PP2A but not IκBα-dependent signals in vascular smooth muscle cells.CARM1 mediates modulation of Sox2.Suppression of dendritic cell-mediated responses by genes in calcium and cysteine protease pathways during Mycobacterium tuberculosis infection.NEMO binds ubiquitinated TANK-binding kinase 1 (TBK1) to regulate innate immune responses to RNA viruses.Characterization and Genetic Analyses of New Genes Coding for NOD2 Interacting ProteinsAndrographolide enhances nuclear factor-kappaB subunit p65 Ser536 dephosphorylation through activation of protein phosphatase 2A in vascular smooth muscle cells.Shigella IpaH0722 E3 ubiquitin ligase effector targets TRAF2 to inhibit PKC-NF-κB activity in invaded epithelial cells.The modulation of phosphatase expression impacts the proliferation efficiency of HSV-1 in infected astrocytes.Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesisGenome-wide siRNA screen for mediators of NF-κB activationStudy of Protein Phosphatase 2A (PP2A) Activity in LPS-Induced Tolerance Using Fluorescence-Based and Immunoprecipitation-Aided Methodology.Homeostatic interactions between MEKK3 and TAK1 involved in NF-kappaB signalingThe role of TRAF2 binding to the type I interferon receptor in alternative NF kappaB activation and antiviral responseThe Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate.TNFR1 signaling kinetics: spatiotemporal control of three phases of IKK activation by posttranslational modification.PHF20 regulates NF-κB signalling by disrupting recruitment of PP2A to p65Insights to transcriptional networks by using high throughput RNAi strategies.Posttranslational modifications of NF-kappaB: another layer of regulation for NF-kappaB signaling pathwayRole of IL-23 in the pathogenesis of psoriasis: a novel potential therapeutic target?Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor fasudil reveals cytoskeletal and pro-survival responses.PP2A as a master regulator of the cell cycle.Merkel cell polyomavirus small T antigen targets the NEMO adaptor protein to disrupt inflammatory signalingUbiquitin ligase CHIP induces TRAF2 proteasomal degradation and NF-κB inactivation to regulate breast cancer cell invasion.The prolyl isomerase Pin1 regulates the NF-kappaB signaling pathway and interleukin-8 expression in glioblastoma.WIP1 phosphatase is a negative regulator of NF-kappaB signalling.The protein phosphatase 2A regulatory subunit B56γ mediates suppression of T cell receptor (TCR)-induced nuclear factor-κB (NF-κB) activity.TRAF2 phosphorylation modulates tumor necrosis factor alpha-induced gene expression and cell resistance to apoptosis.Identification of PP2A as a crucial regulator of the NF-kappaB feedback loop: its inhibition by UVB turns NF-kappaB into a pro-apoptotic factor.
P2860
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P2860
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
description
2006 nî lūn-bûn
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2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年学术文章
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2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
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2006年學術文章
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name
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
@ast
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
@en
RNAi screen in mouse astrocyte ...... regulate NF-kappaB signaling.
@nl
type
label
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
@ast
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
@en
RNAi screen in mouse astrocyte ...... regulate NF-kappaB signaling.
@nl
prefLabel
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
@ast
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
@en
RNAi screen in mouse astrocyte ...... regulate NF-kappaB signaling.
@nl
P2093
P2860
P1433
P1476
RNAi screen in mouse astrocytes identifies phosphatases that regulate NF-kappaB signaling
@en
P2093
Lingyan Wang
Martin E Dorf
Michael A Berman
P2860
P304
P356
10.1016/J.MOLCEL.2006.10.015
P50
P577
2006-11-01T00:00:00Z