Assembly of epithelial tight junctions is negatively regulated by Par6.
about
Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and regulates PKCzeta activityComprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein networkIdentification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivatorCRB3 binds directly to Par6 and regulates the morphogenesis of the tight junctions in mammalian epithelial cellsThe PB1 domain and the PC motif-containing region are structurally similar protein binding modulesTRAF4 Is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell MigrationNephrocystin-1 and nephrocystin-4 are required for epithelial morphogenesis and associate with PALS1/PATJ and Par6Par6 alpha interacts with the dynactin subunit p150 Glued and is a critical regulator of centrosomal protein recruitmentIdentification of the region in Cdc42 that confers the binding specificity to activated Cdc42-associated kinaseIdentification of PKCzetaII: an endogenous inhibitor of cell polarityNon-Smad pathways in TGF-beta signalingExtensions of PDZ domains as important structural and functional elementsSignaling pathways in cell polarity.Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly.Par-3 controls tight junction assembly through the Rac exchange factor Tiam1.Widely conserved signaling pathways in the establishment of cell polarityThe PAR-6 polarity protein regulates dendritic spine morphogenesis through p190 RhoGAP and the Rho GTPase.Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells.The Rac activator Tiam1 controls tight junction biogenesis in keratinocytes through binding to and activation of the Par polarity complexCell polarity regulator PARD6B is essential for trophectoderm formation in the preimplantation mouse embryo.Vertebrate Claudin/PMP22/EMP22/MP20 family protein TMEM47 regulates epithelial cell junction maturation and morphogenesisDaPKC-dependent phosphorylation of Crumbs is required for epithelial cell polarity in Drosophila.Cell adhesion, polarity, and epithelia in the dawn of metazoans.Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6BProtein kinase Czeta regulates Cdk5/p25 signaling during myogenesisPolarity protein complex Scribble/Lgl/Dlg and epithelial cell barriersEstablishment of epithelial polarity--GEF who's minding the GAP?Evidence for a functional interaction between cingulin and ZO-1 in cultured cells.The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer.The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells.Protein complexes that control renal epithelial polarity.The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans.Adaptation of core mechanisms to generate cell polarity.Composition and function of PDZ protein complexes during cell polarization.The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity.Relevance of atypical protein kinase C isotypes to the drug discovery process.Apical targeting of syntaxin 3 is essential for epithelial cell polarity.Expression of JAM-A in the human corneal endothelium and retinal pigment epithelium: localization and evidence for role in barrier function.PAR6B is required for tight junction formation and activated PKCζ localization in breast cancer
P2860
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P2860
Assembly of epithelial tight junctions is negatively regulated by Par6.
description
2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年学术文章
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2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
name
Assembly of epithelial tight junctions is negatively regulated by Par6.
@ast
Assembly of epithelial tight junctions is negatively regulated by Par6.
@en
type
label
Assembly of epithelial tight junctions is negatively regulated by Par6.
@ast
Assembly of epithelial tight junctions is negatively regulated by Par6.
@en
prefLabel
Assembly of epithelial tight junctions is negatively regulated by Par6.
@ast
Assembly of epithelial tight junctions is negatively regulated by Par6.
@en
P2093
P1433
P1476
Assembly of epithelial tight junctions is negatively regulated by Par6.
@en
P2093
Gérard Joberty
Ian G Macara
P304
P356
10.1016/S0960-9822(01)00663-7
P407
P577
2002-02-01T00:00:00Z