Exploring folding free energy landscapes using computational protein design.
about
Synthesizing non-natural parts from natural genomic templateA smoothed backbone-dependent rotamer library for proteins derived from adaptive kernel density estimates and regressionsHigh-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein designProtein folding: then and nowFunctional Class I and II Amino Acid-activating Enzymes Can Be Coded by Opposite Strands of the Same GeneThe Framework of Computational Protein Design.Specific collapse followed by slow hydrogen-bond formation of beta-sheet in the folding of single-chain monellinDiscovery of entry inhibitors for HIV-1 via a new de novo protein design framework.Redesign of the PAK1 autoinhibitory domain for enhanced stability and affinity in biosensor applications.How fast-folding proteins fold.Tracking unfolding and refolding of single GFPmut2 molecules.Energetics and mechanisms of folding and flipping the myristoyl switch in the {beta}-trefoil protein, hisactophilinTwo monoclonal antibodies with defined epitopes of P44 major surface proteins neutralize Anaplasma phagocytophilum by distinct mechanisms.Mutations affecting the oligomerization interface of G-protein-coupled receptors revealed by a novel de novo protein design frameworkTanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy.Knotting and unknotting of a protein in single molecule experiments.Combining multi-mutant and modular thermodynamic cycles to measure energetic coupling networks in enzyme catalysis.Computer-aided design of functional protein interactions.Reversible thermal denaturation of a 60-kDa genetically engineered beta-sheet polypeptide.Folding of apomyoglobin: Analysis of transient intermediate structure during refolding using quick hydrogen deuterium exchange and NMR.Structural insights into conformational stability of wild-type and mutant beta1-adrenergic receptor.The EVB as a quantitative tool for formulating simulations and analyzing biological and chemical reactions.New algorithms and an in silico benchmark for computational enzyme design.Hierarchical cascades of instability govern the mechanics of coiled coils: helix unfolding precedes coil unzipping.Cooperativity and the origins of rapid, single-exponential kinetics in protein folding.Cascaded walks in protein sequence space: use of artificial sequences in remote homology detection between natural proteins.Designing generalized statistical ensembles for numerical simulations of biopolymers.Cell and biomolecular mechanics in silico.Engineering of isoamylase: improvement of protein stability and catalytic efficiency through semi-rational design.The empirical valence bond model: theory and applications
P2860
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P2860
Exploring folding free energy landscapes using computational protein design.
description
2004 nî lūn-bûn
@nan
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Exploring folding free energy landscapes using computational protein design.
@ast
Exploring folding free energy landscapes using computational protein design.
@en
type
label
Exploring folding free energy landscapes using computational protein design.
@ast
Exploring folding free energy landscapes using computational protein design.
@en
prefLabel
Exploring folding free energy landscapes using computational protein design.
@ast
Exploring folding free energy landscapes using computational protein design.
@en
P921
P1476
Exploring folding free energy landscapes using computational protein design.
@en
P356
10.1016/J.SBI.2004.01.002
P577
2004-02-01T00:00:00Z