Computational diagnosis of protein conformational diseases: short molecular dynamics simulations reveal a fast unfolding of r-LDL mutants that cause familial hypercholesterolemia.
about
LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeatQuantitative fluorescence imaging reveals point of release for lipoproteins during LDLR-dependent uptake.A novel 9-bp insertion detected in steroid 21-hydroxylase gene (CYP21A2): prediction of its structural and functional implications by computational methods.Mechanism of low density lipoprotein (LDL) release in the endosome: implications of the stability and Ca2+ affinity of the fifth binding module of the LDL receptor.Exploring the complete mutational space of the LDL receptor LA5 domain using molecular dynamics: linking SNPs with disease phenotypes in familial hypercholesterolemia.PCSK9-mediated degradation of the LDL receptor generates a 17 kDa C-terminal LDL receptor fragment.Scrambled isomers as key intermediates in the oxidative folding of ligand binding module 5 of the low density lipoprotein receptor.Interpreting the Mechanism of APOE (p.Leu167del) Mutation in the Incidence of Familial Hypercholesterolemia; An In-silico Approach.
P2860
Q24321832-4004F0A3-87BE-4CC1-80E9-F7EAE503C120Q36744120-68164D9D-3598-4DBA-AD27-B96EB85A3BE4Q37122776-368ACA06-BD0B-4CFD-80B4-77369E6C10DFQ38289814-D6DC8CD5-293A-4EA9-B6D0-72861839F5C6Q38601708-3C12DFE8-B508-421B-B4C3-D3E14089AF88Q40470485-EBE9C72E-09DF-42E7-BB83-A5116B263381Q46699385-F60A734D-557C-475A-878F-BF18C0102850Q47098616-CC555604-6543-422B-9B69-DBEB8C081B31
P2860
Computational diagnosis of protein conformational diseases: short molecular dynamics simulations reveal a fast unfolding of r-LDL mutants that cause familial hypercholesterolemia.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Computational diagnosis of pro ...... familial hypercholesterolemia.
@ast
Computational diagnosis of pro ...... familial hypercholesterolemia.
@en
type
label
Computational diagnosis of pro ...... familial hypercholesterolemia.
@ast
Computational diagnosis of pro ...... familial hypercholesterolemia.
@en
prefLabel
Computational diagnosis of pro ...... familial hypercholesterolemia.
@ast
Computational diagnosis of pro ...... familial hypercholesterolemia.
@en
P2093
P50
P921
P356
P1433
P1476
Computational diagnosis of pro ...... familial hypercholesterolemia
@en
P2093
P356
10.1002/PROT.21181
P407
P577
2007-01-01T00:00:00Z