Human cytochrome P450 17A1 conformational selection: modulation by ligand and cytochrome b5.
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The Role of Protein-Protein and Protein-Membrane Interactions on P450 FunctionStructures of human steroidogenic cytochrome P450 17A1 with substratesCytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMRStructural insights into the function of steroidogenic cytochrome P450 17A1Role of protein-protein interactions in cytochrome P450-mediated drug metabolism and toxicityResearch Resource: Correlating Human Cytochrome P450 21A2 Crystal Structure and Phenotypes of Mutations in Congenital Adrenal Hyperplasia.Recent Structural Insights into Cytochrome P450 Function.Structural and kinetic basis of steroid 17α,20-lyase activity in teleost fish cytochrome P450 17A1 and its absence in cytochrome P450 17A2.Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.Mechanistic Scrutiny Identifies a Kinetic Role for Cytochrome b5 Regulation of Human Cytochrome P450c17 (CYP17A1, P450 17A1).Spectroscopic studies of the cytochrome P450 reaction mechanisms.The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers.Advances in the Understanding of Protein-Protein Interactions in Drug Metabolizing Enzymes through the Use of Biophysical Techniques.Cytochrome b5 Activates the 17,20-Lyase Activity of Human Cytochrome P450 17A1 by Increasing the Coupling of NADPH Consumption to Androgen Production.Inherent steroid 17α,20-lyase activity in defunct cytochrome P450 17A enzymes.Structural and functional effects of cytochrome b5 interactions with human cytochrome P450 enzymes.Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1.The cytochrome P450 24A1 interaction with adrenodoxin relies on multiple recognition sites that vary among species.Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency.Substrate mediated redox partner selectivity of cytochrome P450
P2860
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P2860
Human cytochrome P450 17A1 conformational selection: modulation by ligand and cytochrome b5.
description
2014 nî lūn-bûn
@nan
2014 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի մարտին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Human cytochrome P450 17A1 con ...... n by ligand and cytochrome b5.
@ast
Human cytochrome P450 17A1 con ...... n by ligand and cytochrome b5.
@en
type
label
Human cytochrome P450 17A1 con ...... n by ligand and cytochrome b5.
@ast
Human cytochrome P450 17A1 con ...... n by ligand and cytochrome b5.
@en
prefLabel
Human cytochrome P450 17A1 con ...... n by ligand and cytochrome b5.
@ast
Human cytochrome P450 17A1 con ...... n by ligand and cytochrome b5.
@en
P2093
P2860
P356
P1476
Human cytochrome P450 17A1 con ...... n by ligand and cytochrome b5.
@en
P2093
Andria L Skinner
D Fernando Estrada
Emily E Scott
Jennifer S Laurence
P2860
P304
14310-14320
P356
10.1074/JBC.M114.560144
P407
P577
2014-03-26T00:00:00Z