A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
about
K-Cl cotransporters, cell volume homeostasis, and neurological diseaseThe Ste20 kinases Ste20-related proline-alanine-rich kinase and oxidative-stress response 1 regulate NKCC1 function in sensory neuronsBehavioral analysis of Ste20 kinase SPAK knockout mice.Rare mutations in renal sodium and potassium transporter genes exhibit impaired transport function.Sites of regulated phosphorylation that control K-Cl cotransporter activityMolecular components of signal amplification in olfactory sensory cilia.A novel Ste20-related proline/alanine-rich kinase (SPAK)-independent pathway involving calcium-binding protein 39 (Cab39) and serine threonine kinase with no lysine member 4 (WNK4) in the activation of Na-K-Cl cotransporters.Multiple pathways for protein phosphatase 1 (PP1) regulation of Na-K-2Cl cotransporter (NKCC1) function: the N-terminal tail of the Na-K-2Cl cotransporter serves as a regulatory scaffold for Ste20-related proline/alanine-rich kinase (SPAK) AND PP1.On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activityHypotonicity stimulates potassium flux through the WNK-SPAK/OSR1 kinase cascade and the Ncc69 sodium-potassium-2-chloride cotransporter in the Drosophila renal tubule.Thick ascending limb of the loop of Henle.Housing and husbandry of Xenopus laevis affect the quality of oocytes for heterologous expression studies.Apoptosis-associated tyrosine kinase scaffolding of protein phosphatase 1 and SPAK reveals a novel pathway for Na-K-2C1 cotransporter regulation.STE20/SPS1-related proline/alanine-rich kinase is involved in plasticity of GABA signaling function in a mouse model of acquired epilepsy.With-No-Lysine Kinase 3 (WNK3) stimulates glioma invasion by regulating cell volumeCritical role of the SPAK protein kinase CCT domain in controlling blood pressureMolecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport.Calcium-binding protein 39 facilitates molecular interaction between Ste20p proline alanine-rich kinase and oxidative stress response 1 monomers.Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.Excitatory actions of GABA in the suprachiasmatic nucleus.Cell volume regulation: physiology and pathophysiology.Sensors, transducers, and effectors that regulate cell size and shape.Physiology and pathophysiology of SLC12A1/2 transporters.The mammalian family of sterile 20p-like protein kinases.Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases.Cell volume homeostatic mechanisms: effectors and signalling pathways.Maintenance and regulation of extracellular volume and the ion environment in Drosophila larval nerves.Role of ion transport in control of apoptotic cell death.Emerging role of WNK1 in pathologic central nervous system signaling.Role of renal transporters and novel regulatory interactions in the TAL that control blood pressure.PKCdelta acts upstream of SPAK in the activation of NKCC1 by hyperosmotic stress in human airway epithelial cells.Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways.Characterization of a novel phosphorylation site in the sodium-chloride cotransporter, NCC.Molecular determinants of hyperosmotically activated NKCC1-mediated K+/K+ exchange.
P2860
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P2860
A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
@ast
A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
@en
type
label
A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
@ast
A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
@en
prefLabel
A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
@ast
A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
@en
P2093
P356
P1476
A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
@en
P2093
Eric Delpire
Kenneth B E Gagnon
Roger England
P304
P356
10.1159/000104161
P577
2007-01-01T00:00:00Z