Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.
about
Reactive Neurogenesis and Down-Regulation of the Potassium-Chloride Cotransporter KCC2 in the Cochlear Nuclei after Cochlear Deafferentation.A noninvasive optical approach for assessing chloride extrusion activity of the K-Cl cotransporter KCC2 in neuronal cells.Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brainChloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential.Cellular compartmentation of energy metabolism: creatine kinase microcompartments and recruitment of B-type creatine kinase to specific subcellular sites.Leveraging unique structural characteristics of WNK kinases to achieve therapeutic inhibition.Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport.Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter.Compromised GABAergic inhibition contributes to tumor-associated epilepsy.GABAA receptor dependent synaptic inhibition rapidly tunes KCC2 activity via the Cl--sensitive WNK1 kinase.The KCC2 Cotransporter and Human Epilepsy: Getting Excited About Inhibition.
P2860
Q30374471-3C9D52CE-3868-4F6A-9743-27487D044085Q36265297-CADEEE0F-F640-4455-8281-4E365304B974Q37366979-FE16AAF1-05B8-4BE9-AA15-27272CEAD249Q38826051-3DB9ADA7-07CC-4822-B75E-9AC4ECE76095Q38869621-32B3ADCA-18F8-4937-A65D-1380AD343D0FQ38997990-744B9F17-10F3-4A99-B379-ABE16670AD90Q39415845-614F782F-9E21-47E1-A05F-D4451594609CQ40989179-CD42506A-C65B-4F99-B5F3-039401801FC3Q41640926-B749E040-2068-4853-81A1-B56C92BBB23DQ47105803-4CF59084-8509-42A1-9186-021CB0C05145Q50312624-015C4D89-EBF9-4C32-977F-EC6214DF38A2
P2860
Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.
@ast
Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.
@en
type
label
Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.
@ast
Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.
@en
prefLabel
Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.
@ast
Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.
@en
P2860
P356
P1476
Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target.
@en
P2093
Eric Delpire
Kristopher T Kahle
P2860
P356
10.1152/JN.00865.2015
P407
P577
2015-10-28T00:00:00Z