DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection.
about
The influenza virus enigmaThe Therapeutic Effect of Pamidronate on Lethal Avian Influenza A H7N9 Virus Infected Humanized MicePrevention of influenza by targeting host receptors using engineered proteinsCompounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part II: Future compounds against influenza virusInhibition of neuraminidase inhibitor-resistant influenza virus by DAS181, a novel sialidase fusion proteinAvian influenza A H5N1 virus: a continuous threat to humans.Two years after pandemic influenza A/2009/H1N1: what have we learned?Impact of Respiratory Virus Infections in Exacerbation of Acute and Chronic Rhinosinusitis.Progress of small molecular inhibitors in the development of anti-influenza virus agents.Investigational hemagglutinin-targeted influenza virus inhibitors.Pathogenesis of 1918 pandemic and H5N1 influenza virus infections in a guinea pig model: antiviral potential of exogenous alpha interferon to reduce virus sheddingInterplay between influenza A virus and host factors: targets for antiviral intervention.Antiviral therapy in seasonal influenza and 2009 H1N1 pandemic influenza: Korean experiences and perspectives.Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein.Networks of Host Factors that Interact with NS1 Protein of Influenza A VirusInfluenza antivirals currently in late-phase clinical trial.Combination chemotherapy for influenza.Antiviral strategies for pandemic and seasonal influenzaPerspective: emerging challenges in the treatment of influenza and parainfluenza in transplant patientsA phase II study of DAS181, a novel host directed antiviral for the treatment of influenza infectionNewer influenza antivirals, biotherapeutics and combinations.Advances in antivirals for non-influenza respiratory virus infections.DAS181 inhibits H5N1 influenza virus infection of human lung tissues.DAS181, a sialidase fusion protein, protects human airway epithelium against influenza virus infection: an in vitro pharmacodynamic analysis.Designing anti-influenza aptamers: novel quantitative structure activity relationship approach gives insights into aptamer-virus interactionInnate immune evasion strategies of influenza virusesAn investigational antiviral drug, DAS181, effectively inhibits replication of zoonotic influenza A virus subtype H7N9 and protects mice from lethality.A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo.Developing new antiviral agents for influenza treatment: what does the future hold?Phenotypic and genotypic characterization of influenza virus mutants selected with the sialidase fusion protein DAS181.New treatments for influenzaAnimal Models for Influenza Virus Pathogenesis and Transmission.Gene silencing of β-galactosamide α-2,6-sialyltransferase 1 inhibits human influenza virus infection of airway epithelial cellsA safety evaluation of DAS181, a sialidase fusion protein, in rodents.Phase 1 clinical trials of DAS181, an inhaled sialidase, in healthy adults.The sweet spot: defining virus-sialic acid interactions.How I treat respiratory viral infections in the setting of intensive chemotherapy or hematopoietic cell transplantationCharacteristics of human infection with avian influenza viruses and development of new antiviral agents.Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections.Drugs to cure avian influenza infection--multiple ways to prevent cell death
P2860
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P2860
DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
name
DAS181, a novel sialidase fusi ...... nfluenza H5N1 virus infection.
@ast
DAS181, a novel sialidase fusi ...... nfluenza H5N1 virus infection.
@en
type
label
DAS181, a novel sialidase fusi ...... nfluenza H5N1 virus infection.
@ast
DAS181, a novel sialidase fusi ...... nfluenza H5N1 virus infection.
@en
prefLabel
DAS181, a novel sialidase fusi ...... nfluenza H5N1 virus infection.
@ast
DAS181, a novel sialidase fusi ...... nfluenza H5N1 virus infection.
@en
P2093
P50
P356
P1476
DAS181, a novel sialidase fusi ...... nfluenza H5N1 virus infection.
@en
P2093
Do Hyong Kim
Laura M Aschenbrenner
Michael P Malakhov
Stephen Hawley
Xiaoping Jin
P304
P356
10.1086/522609
P407
P577
2007-10-31T00:00:00Z