A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo. - Wikidata - awgldk - TriplyDB

A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo.

A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo.

http://www.wikidata.org/entity/Q33936520

about

Management of respiratory viral infections in hematopoietic cell transplant recipients and patients with hematologic malignancies Interaction between the Hemagglutinin-Neuraminidase and Fusion Glycoproteins of Human Parainfluenza Virus Type III Regulates Viral Growth In Vivo The catalytic mechanism of human parainfluenza virus type 3 haemagglutinin-neuraminidase revealed Compounds with anti-influenza activity: present and future of strategies for the optimal treatment and management of influenza. Part II: Future compounds against influenza virus Hospitalization due to human parainfluenza virus-associated lower respiratory tract illness in rural Thailand.The Role of Human Parainfluenza Virus Infections in the Immunopathology of the Respiratory Tract.Perspective: emerging challenges in the treatment of influenza and parainfluenza in transplant patients Emerging antiviral strategies to interfere with influenza virus entry.Newer influenza antivirals, biotherapeutics and combinations.Advances in antivirals for non-influenza respiratory virus infections.Inhibition of Nipah virus infection in vivo: targeting an early stage of paramyxovirus fusion activation during viral entry The impact of the butterfly effect on human parainfluenza virus haemagglutinin-neuraminidase inhibitor design.Circulating clinical strains of human parainfluenza virus reveal viral entry requirements for in vivo infection.Prevention of measles virus infection by intranasal delivery of fusion inhibitor peptides A safety evaluation of DAS181, a sialidase fusion protein, in rodents.Premature activation of the paramyxovirus fusion protein before target cell attachment with corruption of the viral fusion machinery Blood and marrow transplant clinical trials network state of the Science Symposium 2014 DAS181 treatment of hematopoietic stem cell transplant patients with parainfluenza virus lung disease requiring mechanical ventilation Adaptation of human parainfluenza virus to airway epithelium reveals fusion properties required for growth in host tissue.Phase 1 clinical trials of DAS181, an inhaled sialidase, in healthy adults.Parainfluenza virus infections in hematopoietic cell transplant recipients and hematologic malignancy patients: A systematic review DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation.Features of Circulating Parainfluenza Virus Required for Growth in Human Airway.In Vivo Efficacy of Measles Virus Fusion Protein-Derived Peptides Is Modulated by the Properties of Self-Assembly and Membrane Residence.Broad spectrum antiviral activity for paramyxoviruses is modulated by biophysical properties of fusion inhibitory peptides.Viral Respiratory Infections of Adults in the Intensive Care Unit.Update in the treatment of non-influenza respiratory virus infection in solid organ transplant recipients.Structure-guided discovery of potent and dual-acting human parainfluenza virus haemagglutinin-neuraminidase inhibitors.Successful Treatment of Parainfluenza Virus Respiratory Tract Infection With DAS181 in 4 Immunocompromised Children.Inhibition of primary clinical isolates of human parainfluenza virus by DAS181 in cell culture and in a cotton rat model.Human bocavirus 1 infects commercially available primary human airway epithelium cultures productively.DAS181 treatment of severe parainfluenza type 3 pneumonia in a lung transplant recipient.The cotton rat (Sigmodon hispidus) as an animal model for respiratory tract infections with human pathogens.Dynamics of Sendai virus spread, clearance, and immunotherapeutic efficacy after hematopoietic cell transplant imaged non-invasively in mice.Prevalidation of an Acute Inhalation Toxicity Test Using the EpiAirway In Vitro Human Airway Model.Clinical potential of DAS181 for treatment of parainfluenza-3 infections in transplant recipients Treatment of Parainfluenza 3 Infection With DAS181 in a Patient After Allogeneic Stem Cell Transplantation

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P2860

A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo.

http://www.wikidata.org/entity/Q33936520

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

A recombinant sialidase fusion ...... nfection in vitro and in vivo.

@ast

A recombinant sialidase fusion ...... nfection in vitro and in vivo.

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type

label

A recombinant sialidase fusion ...... nfection in vitro and in vivo.

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A recombinant sialidase fusion ...... nfection in vitro and in vivo.

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prefLabel

A recombinant sialidase fusion ...... nfection in vitro and in vivo.

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A recombinant sialidase fusion ...... nfection in vitro and in vivo.

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P2860

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P1433

The Journal of Infectious Diseases

P1476

A recombinant sialidase fusion ...... nfection in vitro and in vivo.

@en

P2093

Anne Moscona

http://www.w3.org/2001/XMLSchema#string

Caroline Tai

http://www.w3.org/2001/XMLSchema#string

David Wurtman

http://www.w3.org/2001/XMLSchema#string

Fang Fang

http://www.w3.org/2001/XMLSchema#string

Gallen Triana-Baltzer

http://www.w3.org/2001/XMLSchema#string

Lori Aschenbrenner

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Matteo Porotto

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Qi-Xiang Li

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Samantha Palmer

http://www.w3.org/2001/XMLSchema#string

Stefan Niewiesk

http://www.w3.org/2001/XMLSchema#string

P2860

Entry of parainfluenza virus into cells as a target for interrupting childhood respiratory disease

Mutations in human parainfluenza virus type 3 hemagglutinin-neuraminidase causing increased receptor binding activity and resistance to the transition state sialic acid analog 4-GU-DANA (Zanamivir).

The anti-influenza virus agent 4-GU-DANA (zanamivir) inhibits cell fusion mediated by human parainfluenza virus and influenza virus HA.

Human and avian influenza viruses target different cell types in cultures of human airway epithelium.

Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection.

Medical management of influenza infection.

DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection.

DAS181, a sialidase fusion protein, protects human airway epithelium against influenza virus infection: an in vitro pharmacodynamic analysis.

Receptor specificities of human respiroviruses.

Contribution of the human parainfluenza virus type 3 HN-receptor interaction to pathogenesis in vivo.

P304

234-241

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scholarly article

P356

10.1086/653621

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P407

P433

2

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P478

202

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P577

2010-07-01T00:00:00Z

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P5875

44659506

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P698

20533871

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P921

membrane fusion involved in viral entry into host cell

P932

2891144

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