Four human thiopurine s-methyltransferase alleles severely affect protein structure and dynamics
about
Assessment of Thiopurine-based drugs according to Thiopurine S-methyltransferase genotype in patients with Acute Lymphoblastic LeukemiaInsight into TPMT(∗)23 mutation mis-folding using molecular dynamics simulation and protein structure analysis.Dynameomics: a comprehensive database of protein dynamics.Polymorphisms and disease: hotspots of inactivation in methyltransferasesClinical implication of thiopurine methyltransferase polymorphism in children with acute lymphoblastic leukemia: A preliminary Egyptian study.Thiopurine methyltransferase genotype-phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia.The R46Q, R131Q and R154H polymorphs of human DNA glycosylase/beta-lyase hOgg1 severely distort the active site and DNA recognition site but do not cause unfolding.Single nucleotide polymorphism and its dynamics for pharmacogenomics.TPMT Polymorphism: When Shield Becomes Weakness.One amino acid makes a difference-Characterization of a new TPMT allele and the influence of SAM on TPMT stability.Frequency of thiopurine S-methyltransferase (TPMT) alleles in southeast Iranian population.In Vitro Protein Stability of Two Naturally Occurring Thiopurine S-Methyltransferase Variants: Biophysical Characterization of TPMT*6 and TPMT*8.
P2860
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P2860
Four human thiopurine s-methyltransferase alleles severely affect protein structure and dynamics
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Four human thiopurine s-methyl ...... protein structure and dynamics
@ast
Four human thiopurine s-methyl ...... protein structure and dynamics
@en
type
label
Four human thiopurine s-methyl ...... protein structure and dynamics
@ast
Four human thiopurine s-methyl ...... protein structure and dynamics
@en
prefLabel
Four human thiopurine s-methyl ...... protein structure and dynamics
@ast
Four human thiopurine s-methyl ...... protein structure and dynamics
@en
P2860
P1476
Four human thiopurine s-methyl ...... protein structure and dynamics
@en
P2093
Karen Rutherford
P2860
P304
P356
10.1016/J.JMB.2008.04.032
P407
P577
2008-04-18T00:00:00Z