Contributions of ionic interactions and protein dynamics to cytochrome P450 2D6 (CYP2D6) substrate and inhibitor binding.

Contributions of ionic interactions and protein dynamics to cytochrome P450 2D6 (CYP2D6) substrate and inhibitor binding.

Item
http://www.wikidata.org/entity/Q30370390
Variation in Human Cytochrome P-450 Drug-Metabolism Genes: A Gateway to the Understanding of Plasmodium vivax RelapsesIntegrated structure- and ligand-based in silico approach to predict inhibition of cytochrome P450 2D6.Recent Structural Insights into Cytochrome P450 Function.Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitors.NADH reduction of nitroaromatics as a probe for residual ferric form high-spin in a cytochrome P450.Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugs.Cytochrome P450 structure-function: insights from molecular dynamics simulations.A combinatorial approach for the discovery of cytochrome P450 2D6 inhibitors from nature.Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry.Solution Conformations and Dynamics of Substrate-Bound Cytochrome P450 MycG.Cytochrome P450 2D6 and Parkinson's Disease: Polymorphism, Metabolic Role, Risk and Protection.Reactivity Patterns of (Protonated) Compound II and Compound I of Cytochrome P450: Which is the Better Oxidant?Molecular Determinants of Substrate Affinity and Enzyme Activity of a Cytochrome P450 VariantMicrosecond MD simulations of human CYP2D6 wild-type and five allelic variants reveal mechanistic insights on the function
P2860

Contributions of ionic interactions and protein dynamics to cytochrome P450 2D6 (CYP2D6) substrate and inhibitor binding.

Item
http://www.wikidata.org/entity/Q30370390
description
2015 nî lūn-bûn
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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Contributions of ionic interac ...... bstrate and inhibitor binding.
@ast
Contributions of ionic interac ...... bstrate and inhibitor binding.
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type
label
Contributions of ionic interac ...... bstrate and inhibitor binding.
@ast
Contributions of ionic interac ...... bstrate and inhibitor binding.
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prefLabel
Contributions of ionic interac ...... bstrate and inhibitor binding.
@ast
Contributions of ionic interac ...... bstrate and inhibitor binding.
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P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Contributions of ionic interac ...... bstrate and inhibitor binding.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932