Substitution of lysine at 627 position in PB2 protein does not change virulence of the 2009 pandemic H1N1 virus in mice
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Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza VirusPathogenicity and transmissibility of North American triple reassortant swine influenza A viruses in ferretsImproving pandemic influenza risk assessment.Infectivity and Transmissibility of Avian H9N2 Influenza Viruses in Pigs.Two years after pandemic influenza A/2009/H1N1: what have we learned?PB2-588I enhances 2009 H1N1 pandemic influenza virus virulence by increasing viral replication and exacerbating PB2 inhibition of beta interferon expression.Differences in transmissibility and pathogenicity of reassortants between H9N2 and 2009 pandemic H1N1 influenza A viruses from humans and swine.Naturally occurring mutations in the PA gene are key contributors to increased virulence of pandemic H1N1/09 influenza virus in mice.Analysis of recombinant H7N9 wild-type and mutant viruses in pigs shows that the Q226L mutation in HA is important for transmissionMutations associated with severity of the pandemic influenza A(H1N1)pdm09 in humans: a systematic review and meta-analysis of epidemiological evidence.PB2 residue 158 is a pathogenic determinant of pandemic H1N1 and H5 influenza a viruses in mice.Genetic and antigenic characterization of H1 influenza viruses from United States swine from 2008.Atypical characteristics of nucleoprotein of pandemic influenza virus H1N1 and their roles in reassortment restriction.The first influenza pandemic of the new millennium.Virulence and genetic compatibility of polymerase reassortant viruses derived from the pandemic (H1N1) 2009 influenza virus and circulating influenza A viruses.Genomic polymorphism of the pandemic A (H1N1) influenza viruses correlates with viral replication, virulence, and pathogenicity in vitro and in vivoHemagglutinin-neuraminidase balance confers respiratory-droplet transmissibility of the pandemic H1N1 influenza virus in ferrets.Novel reassortment of Eurasian avian-like and pandemic/2009 influenza viruses in swine: infectious potential for humans.Combination of PB2 271A and SR polymorphism at positions 590/591 is critical for viral replication and virulence of swine influenza virus in cultured cells and in vivoAsparagine substitution at PB2 residue 701 enhances the replication, pathogenicity, and transmission of the 2009 pandemic H1N1 influenza A virus.Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.Characterization of an H3N2 triple reassortant influenza virus with a mutation at the receptor binding domain (D190A) that occurred upon virus transmission from turkeys to pigs.Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig modelsThe K526R substitution in viral protein PB2 enhances the effects of E627K on influenza virus replication.Evaluation of MDCK cell-derived influenza H7N9 vaccine candidates in ferretsInfluence of PB2 host-range determinants on the intranuclear mobility of the influenza A virus polymerase.Role of H7 hemagglutinin in murine infectivity of influenza viruses following ocular inoculation.Identification of a highly conserved and surface exposed B-cell epitope on the nucleoprotein of influenza A virus.Multiple clusters of A(H1N1)pdm09 virus circulating in severe cases of influenza during the 2010-2011 season: a phylogenetic and molecular analysis of the neuraminidase gene.Zoonotic Potential of Influenza A Viruses: A Comprehensive Overview
P2860
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P2860
Substitution of lysine at 627 position in PB2 protein does not change virulence of the 2009 pandemic H1N1 virus in mice
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Substitution of lysine at 627 ...... 09 pandemic H1N1 virus in mice
@ast
Substitution of lysine at 627 ...... 09 pandemic H1N1 virus in mice
@en
type
label
Substitution of lysine at 627 ...... 09 pandemic H1N1 virus in mice
@ast
Substitution of lysine at 627 ...... 09 pandemic H1N1 virus in mice
@en
prefLabel
Substitution of lysine at 627 ...... 09 pandemic H1N1 virus in mice
@ast
Substitution of lysine at 627 ...... 09 pandemic H1N1 virus in mice
@en
P2093
P2860
P50
P1433
P1476
Substitution of lysine at 627 ...... 09 pandemic H1N1 virus in mice
@en
P2093
Honglin Chen
Kunyuan Guo
Rirong Chen
Taixing Zhang
Wenjun Song
Zuoyi Zheng
P2860
P356
10.1016/J.VIROL.2010.02.024
P407
P577
2010-03-19T00:00:00Z