Multidrug-resistant 2009 pandemic influenza A(H1N1) viruses maintain fitness and transmissibility in ferrets.
about
Prolonged influenza virus shedding and emergence of antiviral resistance in immunocompromised patients and ferrets3-Hydroxyquinolin-2(1 H )-ones As Inhibitors of Influenza A EndonucleaseEngineering H5N1 avian influenza viruses to study human adaptationInfluenza viruses: breaking all the rulesEstimating the fitness advantage conferred by permissive neuraminidase mutations in recent oseltamivir-resistant A(H1N1)pdm09 influenza virusesTwo years after pandemic influenza A/2009/H1N1: what have we learned?Phenyl substituted 4-hydroxypyridazin-3(2H)-ones and 5-hydroxypyrimidin-4(3H)-ones: inhibitors of influenza A endonuclease.Profiling and characterization of influenza virus N1 strains potentially resistant to multiple neuraminidase inhibitors.Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism.A Novel Endonuclease Inhibitor Exhibits Broad-Spectrum Anti-Influenza Virus Activity In VitroA computational-experimental approach identifies mutations that enhance surface expression of an oseltamivir-resistant influenza neuraminidase.The host interactome of influenza virus presents new potential targets for antiviral drugs.Multidrug resistant 2009 A/H1N1 influenza clinical isolate with a neuraminidase I223R mutation retains its virulence and transmissibility in ferretsEfficient transmission of pandemic H1N1 influenza viruses with high-level oseltamivir resistanceDecreased neuraminidase activity is important for the adaptation of H5N1 influenza virus to human airway epithelium.Fitness of neuraminidase inhibitor-resistant influenza A virusesComparable fitness and transmissibility between oseltamivir-resistant pandemic 2009 and seasonal H1N1 influenza viruses with the H275Y neuraminidase mutation.The H275Y neuraminidase mutation of the pandemic A/H1N1 influenza virus lengthens the eclipse phase and reduces viral output of infected cells, potentially compromising fitness in ferrets.Consequences of resistance: in vitro fitness, in vivo infectivity, and transmissibility of oseltamivir-resistant influenza A viruses.Evaluation of recombinant 2009 pandemic influenza A (H1N1) viruses harboring zanamivir resistance mutations in mice and ferrets.Decoding the distribution of glycan receptors for human-adapted influenza A viruses in ferret respiratory tract.Structural characterization of a protective epitope spanning A(H1N1)pdm09 influenza virus neuraminidase monomers.Influenza neuraminidase.In vivo evaluation of pathogenicity and transmissibility of influenza A(H1N1)pdm09 hemagglutinin receptor binding domain 222 intrahost variants isolated from a single immunocompromised patientAntigen-activated dendritic cells ameliorate influenza A infectionsN-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes.Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility.Impact of potential permissive neuraminidase mutations on viral fitness of the H275Y oseltamivir-resistant influenza A(H1N1)pdm09 virus in vitro, in mice and in ferrets.Using mutagenesis to explore conserved residues in the RNA-binding groove of influenza A virus nucleoprotein for antiviral drug development.Investigation of the salicylaldehyde thiosemicarbazone scaffold for inhibition of influenza virus PA endonuclease.Porphyrin-based cationic amphiphilic photosensitisers as potential anticancer, antimicrobial and immunosuppressive agentsCharacterization of drug-resistant influenza A(H7N9) variants isolated from an oseltamivir-treated patient in Taiwan.
P2860
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P2860
Multidrug-resistant 2009 pandemic influenza A(H1N1) viruses maintain fitness and transmissibility in ferrets.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Multidrug-resistant 2009 pande ...... d transmissibility in ferrets.
@ast
Multidrug-resistant 2009 pande ...... d transmissibility in ferrets.
@en
type
label
Multidrug-resistant 2009 pande ...... d transmissibility in ferrets.
@ast
Multidrug-resistant 2009 pande ...... d transmissibility in ferrets.
@en
prefLabel
Multidrug-resistant 2009 pande ...... d transmissibility in ferrets.
@ast
Multidrug-resistant 2009 pande ...... d transmissibility in ferrets.
@en
P2093
P2860
P356
P1476
Multidrug-resistant 2009 pande ...... d transmissibility in ferrets.
@en
P2093
A Sally Davis
Daniel S Chertow
Kathleen Proudfoot
Rachel J Hrabal
Tyler Bristol
P2860
P304
P356
10.1093/INFDIS/JIQ067
P407
P577
2010-12-20T00:00:00Z