Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit
about
Modulation of neuronal signal transduction and memory formation by synaptic zincZinc involvement in opioid addiction and analgesia--should zinc supplementation be recommended for opioid-treated persons?Redox and trace metal regulation of ion channels in the pain pathwayModulation of extrasynaptic NMDA receptors by synaptic and tonic zinc.Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout miceTonic zinc inhibits spontaneous firing in dorsal cochlear nucleus principal neurons by enhancing glycinergic neurotransmission.Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis.The Link between Depression and Chronic Pain: Neural Mechanisms in the Brain.Interaction between Analgesic Effect of Nano and Conventional size of Zinc Oxide and Opioidergic System Activity in Animal Model of Acute PainZinc-permeable ion channels: effects on intracellular zinc dynamics and potential physiological/pathophysiological significance.The neurophysiology and pathology of brain zinc.Altered Levels of Zinc and N-methyl-D-aspartic Acid Receptor Underlying Multiple Organ Dysfunctions After Severe Trauma.Inhibition of human acid-sensing ion channel 1b by zincExtracellular zinc ion regulates transient receptor potential melastatin 5 (TRPM5) channel activation through its interaction with a pore loop domain.Endogenous zinc depresses GABAergic transmission via T-type Ca(2+) channels and broadens the time window for integration of glutamatergic inputs in dentate granule cells.ON or OFF?: Modulating the N-Methyl-D-Aspartate Receptor in Major Depression.Metalloneurochemistry and the Pierian Spring: 'Shallow Draughts Intoxicate the Brain'.Deconstructing the neuropathic pain phenotype to reveal neural mechanisms.Emerging approaches to probing ion channel structure and function.Contribution of calcium-conducting channels to the transport of zinc ions.Distinct functional and pharmacological properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA receptors.The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism.NMDA receptors: linking physiological output to biophysical operation.Genetic alteration of the metal/redox modulation of Cav3.2 T-type calcium channel reveals its role in neuronal excitability.Metaplasticity gated through differential regulation of GluN2A versus GluN2B receptors by Src family kinases.Molecular Basis for Subtype Specificity and High-Affinity Zinc Inhibition in the GluN1-GluN2A NMDA Receptor Amino-Terminal Domain.Triheteromeric NMDA receptors at hippocampal synapses.Group II metabotropic glutamate receptors modify N-methyl-D-aspartate receptors via Src kinase.Common trace elements alleviate pain in an experimental mouse model.Understanding the Contribution of Zinc Transporters in the Function of the Early Secretory Pathway.Zinc Inhibits TRPV1 to Alleviate Chemotherapy-Induced Neuropathic Pain.Activity-dependent control of NMDA receptor subunit composition at hippocampal mossy fibre synapses.Enhanced analgesic effects of tramadol and common trace element coadministration in mice.Zinc transporter-1: a novel NMDA receptor-binding protein at the postsynaptic density.Experimental Research Showing the Reduction of Naloxone-Place Aversion by Oral Zinc Administration in Rats.Zinc deficiency causes delayed ATP clearance and adenosine generation in rats and cell culture models
P2860
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P2860
Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit
@ast
Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit
@en
type
label
Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit
@ast
Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit
@en
prefLabel
Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit
@ast
Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit
@en
P2093
P2860
P356
P1433
P1476
Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit
@en
P2093
Abdel-Mouttalib Ouagazzal
Angela Maria Vergnano
Anne Le Goff
Brigitte L Kieffer
Chihiro Nozaki
Claire Gaveriaux-Ruff
David Reiss
Dominique Filliol
Jacques Neyton
Pierre Paoletti
P2860
P2888
P304
P356
10.1038/NN.2844
P407
P577
2011-07-03T00:00:00Z