A single direct injection into the left ventricular wall of an adeno-associated virus 9 (AAV9) vector expressing extracellular superoxide dismutase from the cardiac troponin-T promoter protects mice against myocardial infarction.
about
Gene therapy for cardiovascular disease: advances in vector development, targeting, and delivery for clinical translationOptogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability.Systemic injection of AAV9 carrying a periostin promoter targets gene expression to a myofibroblast-like lineage in mouse hearts after reperfused myocardial infarction.Extracellular superoxide dismutase ameliorates skeletal muscle abnormalities, cachexia, and exercise intolerance in mice with congestive heart failure.Cardiac-selective expression of extracellular superoxide dismutase after systemic injection of adeno-associated virus 9 protects the heart against post-myocardial infarction left ventricular remodeling.Adeno-associated virus serotype 9 administered systemically after reperfusion preferentially targets cardiomyocytes in the infarct border zone with pharmacodynamics suitable for the attenuation of left ventricular remodeling.Opposing role for Egr3 in nucleus accumbens cell subtypes in cocaine action.Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulationsEnhancing the utility of adeno-associated virus gene transfer through inducible tissue-specific expression.An emerging adeno-associated viral vector pipeline for cardiac gene therapyA comprehensive multiscale framework for simulating optogenetics in the heart.See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?Cardiac applications of optogenetics."Beauty is a light in the heart": the transformative potential of optogenetics for clinical applications in cardiovascular medicine.The dual effect of ultrasound-targeted microbubble destruction in mediating recombinant adeno-associated virus delivery in renal cell carcinoma: transfection enhancement and tumor inhibition.MicroRNAs: pleiotropic players in congenital heart disease and regeneration.Synergistic cardioprotective effects of rAAV9-CyclinA2 combined with fibrin glue in rats after myocardial infarction.Optogenetic termination of ventricular arrhythmias in the whole heart: towards biological cardiac rhythm management.Efficacy and safety of myocardial gene transfer of adenovirus, adeno-associated virus and lentivirus vectors in the mouse heart.Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach.Muscle-derived extracellular superoxide dismutase inhibits endothelial activation and protects against multiple organ dysfunction syndrome in mice.Drp1 Mitochondrial Fission in D1 Neurons Mediates Behavioral and Cellular Plasticity during Early Cocaine Abstinence.Intramuscular Adeno-Associated Virus-Mediated Expression of Monoclonal Antibodies Provides 100% Protection Against Ebola Virus Infection in Mice.Molecular basis of dendritic atrophy and activity in stress susceptibility.Non-invasive detection of adeno-associated viral gene transfer using a genetically encoded CEST-MRI reporter gene in the murine heart.
P2860
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P2860
A single direct injection into the left ventricular wall of an adeno-associated virus 9 (AAV9) vector expressing extracellular superoxide dismutase from the cardiac troponin-T promoter protects mice against myocardial infarction.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A single direct injection into ...... against myocardial infarction.
@ast
A single direct injection into ...... against myocardial infarction.
@en
type
label
A single direct injection into ...... against myocardial infarction.
@ast
A single direct injection into ...... against myocardial infarction.
@en
prefLabel
A single direct injection into ...... against myocardial infarction.
@ast
A single direct injection into ...... against myocardial infarction.
@en
P2860
P50
P356
P1476
A single direct injection into ...... against myocardial infarction.
@en
P2093
Robert S Smith
P2860
P304
P356
10.1002/JGM.1576
P577
2011-06-01T00:00:00Z