A comprehensive multiscale framework for simulating optogenetics in the heart.
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Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability.Light-based Approaches to Cardiac Arrhythmia Research: From Basic Science to Translational ApplicationsImages as drivers of progress in cardiac computational modelling.Optogenetic defibrillation terminates ventricular arrhythmia in mouse hearts and human simulations.Optogenetic Control of Heart Rhythm by Selective Stimulation of Cardiomyocytes Derived from Pnmt+ Cells in Murine Heart.Optical mapping of optogenetically shaped cardiac action potentialsExploring susceptibility to atrial and ventricular arrhythmias resulting from remodeling of the passive electrical properties in the heart: a simulation approachMethodology for image-based reconstruction of ventricular geometry for patient-specific modeling of cardiac electrophysiology.Optogenetic versus Electrical Stimulation of Human Cardiomyocytes: Modeling InsightsOptogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2.PyRhO: A Multiscale Optogenetics Simulation PlatformComputational modeling of cardiac optogenetics: Methodology overview & review of findings from simulationsDetermining Cardiac Fiber Orientation Using FSL and Registered Ultrasound/DTI volumes.A review of the literature on cardiac electrical activity between fibroblasts and myocytes.Early somatic mosaicism is a rare cause of long-QT syndrome.See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?Advances in modeling ventricular arrhythmias: from mechanisms to the clinic.Cardiac applications of optogenetics.Toward microendoscopy-inspired cardiac optogenetics in vivo: technical overview and perspective."Beauty is a light in the heart": the transformative potential of optogenetics for clinical applications in cardiovascular medicine.Concise Review: Fluorescent Reporters in Human Pluripotent Stem Cells: Contributions to Cardiac Differentiation and Their Applications in Cardiac Disease and Toxicity.How computer simulations of the human heart can improve anti-arrhythmia therapy.Computational rabbit models to investigate the initiation, perpetuation, and termination of ventricular arrhythmia.Modulation of cardiac tissue electrophysiological properties with light-sensitive proteins.Optogenetics' promise: pacing and cardioversion by light?Optogenetic termination of ventricular arrhythmias in the whole heart: towards biological cardiac rhythm management.All-optical control of cardiac excitation: combined high-resolution optogenetic actuation and optical mapping.Neural Crest Stem Cells Can Differentiate to a Cardiomyogenic Lineage with an Ability to Contract in Response to Pulsed Infrared Stimulation.Optogenetics-enabled dynamic modulation of action potential duration in atrial tissue: feasibility of a novel therapeutic approach.Channelrhodopsin2 current during the action potential: "optical AP clamp" and approximation.Fiat lux in understanding cardiac pacing, resynchronization and signalling by way of optogeneticsAcute Optogenetic Modulation of Cardiac Twitch Dynamics Explored Through ModelingCardiac neuroanatomy - Imaging nerves to define functional control.Termination of re-entrant atrial tachycardia via optogenetic stimulation with optimized spatial targeting: insights from computational models.Optogenetics and pharmacogenetics: principles and applications.Opsin spectral sensitivity determines the effectiveness of optogenetic termination of ventricular fibrillation in the human heart: a simulation study.Using personalized computer models to custom-tailor ablation procedures for atrial fibrillation patients: are we there yet?Neuronal gain modulability is determined by dendritic morphology: A computational optogenetic study.Dynamics of neuroeffector coupling at cardiac sympathetic synapses.Real-time optical manipulation of cardiac conduction in intact hearts
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A comprehensive multiscale framework for simulating optogenetics in the heart.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2013
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
A comprehensive multiscale framework for simulating optogenetics in the heart.
@en
A comprehensive multiscale framework for simulating optogenetics in the heart.
@nl
type
label
A comprehensive multiscale framework for simulating optogenetics in the heart.
@en
A comprehensive multiscale framework for simulating optogenetics in the heart.
@nl
prefLabel
A comprehensive multiscale framework for simulating optogenetics in the heart.
@en
A comprehensive multiscale framework for simulating optogenetics in the heart.
@nl
P2860
P50
P356
P1476
A comprehensive multiscale framework for simulating optogenetics in the heart
@en
P2093
Christina M Ambrosi
Emilia Entcheva
P2860
P2888
P356
10.1038/NCOMMS3370
P407
P577
2013-01-01T00:00:00Z