Regulation of osteoclast structure and function by FAK family kinases - Wikidata - awgldk - TriplyDB

Regulation of osteoclast structure and function by FAK family kinases

Regulation of osteoclast structure and function by FAK family kinases

http://www.wikidata.org/entity/Q30416629

about

DC-STAMP: A Key Regulator in Osteoclast Differentiation Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangements Focal adhesion kinase is required for synovial fibroblast invasion, but not murine inflammatory arthritis Noncanonical G-protein-dependent modulation of osteoclast differentiation and bone resorption mediated by Pasteurella multocida toxin Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1.An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2.The nonreceptor protein tyrosine kinase Pyk2 promotes the turnover of monocytes at steady state.Tissue-specific pathway association analysis using genome-wide association study summaries.Sperm-oocyte contact induces outside-in signaling via PYK2 activation.A 15-amino acid C-terminal peptide of beta-defensin-3 inhibits bone resorption by inhibiting the osteoclast differentiation and disrupting podosome belt formation.

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P2860

Regulation of osteoclast structure and function by FAK family kinases

http://www.wikidata.org/entity/Q30416629

description

2012 nî lūn-bûn

@nan

2012 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Regulation of osteoclast structure and function by FAK family kinases

@ast

Regulation of osteoclast structure and function by FAK family kinases

@en

type

label

Regulation of osteoclast structure and function by FAK family kinases

@ast

Regulation of osteoclast structure and function by FAK family kinases

@en

prefLabel

Regulation of osteoclast structure and function by FAK family kinases

@ast

Regulation of osteoclast structure and function by FAK family kinases

@en

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P1433

Journal of Leukocyte Biology

P1476

Regulation of osteoclast structure and function by FAK family kinases

@en

P2093

Amy H Bouton

http://www.w3.org/2001/XMLSchema#string

Brianne J Ray

http://www.w3.org/2001/XMLSchema#string

Cynthia S Huang

http://www.w3.org/2001/XMLSchema#string

Keena Thomas

http://www.w3.org/2001/XMLSchema#string

Michael F Gutknecht

http://www.w3.org/2001/XMLSchema#string

P2860

Cbl associates with Pyk2 and Src to regulate Src kinase activity, alpha(v)beta(3) integrin-mediated signaling, cell adhesion, and osteoclast motility

Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein.

Bone resorption by osteoclasts

Signaling through focal adhesion kinase

Involvement of the Src-cortactin pathway in podosome formation and turnover during polarization of cultured osteoclasts

The molecular dynamics of osteoclast adhesions

Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.

Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration.

Proline-rich tyrosine kinase 2 regulates osteoprogenitor cells and bone formation, and offers an anabolic treatment approach for osteoporosis.

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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1021-1028

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scholarly article

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10.1189/JLB.0512259

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5

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92

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Edward A Botchwey

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2012-08-31T00:00:00Z

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230783763

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22941736

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3476245

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