Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction
about
Genetic susceptibility to lung cancer and co-morbiditiesAirway remodelling in COPD: It's not asthma!Candidate genes for COPD: current evidence and researchTargeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunitiesAPOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema.Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.Integrative pathway genomics of lung function and airflow obstruction.Genome-wide study of percent emphysema on computed tomography in the general population. The Multi-Ethnic Study of Atherosclerosis Lung/SNP Health Association Resource Study.Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.Neuroendocrine signaling via the serotonin transporter regulates clearance of apoptotic cells.Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan.Two CHRN susceptibility variants for COPD are genetic determinants of emphysema and chest computed tomography manifestations in Chinese patients.Molecular processes that drive cigarette smoke-induced epithelial cell fate of the lung.Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery diseaseADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing StudyIntegrative genomics of chronic obstructive pulmonary disease.Beyond cigarettes per day. A genome-wide association study of the biomarker carbon monoxide.Recent updates on electronic cigarette aerosol and inhaled nicotine effects on periodontal and pulmonary tissues.Genetic variation in HTR4 and lung function: GWAS follow-up in mouse.Elevated serum iron is a potent biomarker for spirometric resistance to cigarette smoke among Japanese males: the Takahata studyCis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry.Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung functionIREB2 and GALC are associated with pulmonary artery enlargement in chronic obstructive pulmonary diseaseGene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline.A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.Role of Lung Function Genes in the Development of AsthmaA multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence.Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank.A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging PhenotypesTargeted Sequencing of Lung Function Loci in Chronic Obstructive Pulmonary Disease Cases and Controls.Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputationWhole exome sequencing identifies novel candidate genes that modify chronic obstructive pulmonary disease susceptibility.The role of WWOX polymorphisms on COPD susceptibility and pulmonary function traits in Chinese: a case-control study and family-based analysisDissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility.Genetic control of gene expression at novel and established chronic obstructive pulmonary disease lociNicotinic acetylcholine receptor expression in human airway correlates with lung function.Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.
P2860
Q24606717-81072BAF-3E7A-47D5-822D-9C52712FF68EQ26744402-CCDA99FA-D78A-4F18-B1FF-9F0D78167511Q26777324-82DC90FF-FD8E-42A5-96FB-1B531B18EE4CQ27027433-04C90F05-FB05-4B93-9F0B-118CE19294D6Q28387051-A62F7981-59D1-4E98-B1C4-09CE8907F21BQ29416987-D2133088-EA22-449E-916F-21BDADF2F7FCQ30274832-89B99C6D-55DE-4ABC-8539-BFD409F6893FQ30278644-85622651-846C-4882-BA39-54D268599DA4Q30408059-A685F584-33E3-4279-BB04-EF1D8F763AE3Q31129874-E86242F5-E89C-4943-965E-6955B5C66A1EQ33553057-97C71B43-E4C8-45A4-B752-FDD8D9CE4592Q33675710-EA3D65C4-1056-4D63-90BA-DA32FFC76FE2Q33707773-1F69393D-59E6-4BBF-8A9F-4ED8026D67B3Q33713727-267835B6-E19B-4BFD-921F-0562B8090AE8Q33799686-92CF0DB8-8F8D-4B8F-8DE6-B885E3497602Q33830476-98A3349F-31CE-49C2-AA4A-E75AAF5D56DDQ34004971-F2AD15E3-5BAD-4A46-96ED-8C84872941FFQ34060246-7DD8A144-8595-4DD5-8C37-FE92BF5F7929Q34232677-1FD732DB-200A-4E9F-9E50-13C28B17B638Q34425646-1DE716F8-293C-48D0-BB5A-54950BD36D20Q34550739-23177189-78AC-40C0-9E73-388C5F9F3775Q34847876-F1E56B38-55F6-4665-AB11-BACDDA59E8D7Q34989644-D789D843-6064-4EF9-8009-E2BE89EF5A95Q35058477-C2F25FD9-8E78-4E67-A3BF-25CE2EF6BA35Q35156969-859C9F55-DBEF-4B52-ABDE-259615560A04Q35207735-7C0D863D-A928-4B58-9255-E2F86406769DQ35595026-D73D5314-128C-4DF3-8BBC-297598DEFE72Q35860362-32C1127C-7085-4D39-A396-35C8F168AF2EQ35890486-7A81B365-3DA4-4E4D-A761-D604902BD4CFQ36089387-0D69DB7F-62C8-4C0E-B7FF-1E8F0E60C8C8Q36123192-EC4AA3D5-B47E-45C8-AEF1-CEC4F1D2F112Q36128611-FBD84864-27FA-47A6-B46F-C34D076B94E1Q36257364-22996D22-0D39-48D5-BA70-95B622F3B027Q36392496-43390253-9D8E-48CD-95DD-8E9D94FF5359Q36443195-1138129E-1188-487C-8EEF-E68769ACF3DAQ36605892-F2BC3BFF-8F1D-4342-BC77-B46A875BE037Q36691602-DFFB0E64-DD3E-4B0E-B7A5-B1991C6AF83EQ36724956-A4858E8A-F623-42AF-BE03-D377C67E993DQ36955313-2605675D-06D0-4FAE-B49F-729653E2FD60Q36968835-7358775B-3550-4ED6-87AD-CB5FCB4524CD
P2860
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction
description
2012 nî lūn-bûn
@nan
2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Genome-wide association studie ...... lopment of airflow obstruction
@ast
Genome-wide association studie ...... lopment of airflow obstruction
@en
type
label
Genome-wide association studie ...... lopment of airflow obstruction
@ast
Genome-wide association studie ...... lopment of airflow obstruction
@en
prefLabel
Genome-wide association studie ...... lopment of airflow obstruction
@ast
Genome-wide association studie ...... lopment of airflow obstruction
@en
P2093
P2860
P50
P1476
Genome-wide association studie ...... lopment of airflow obstruction
@en
P2093
Alan L James
Amund Gulsvik
Amy R Bentley
Arthur W Musk
Bruno H Stricker
Daan W Loth
David A Lomas
David Couper
David P Strachan
Edwin K Silverman
P2860
P304
P356
10.1164/RCCM.201202-0366OC
P407
P50
P577
2012-07-26T00:00:00Z