Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. - Wikidata - awgldk - TriplyDB

Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling.

Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling.

http://www.wikidata.org/entity/Q30432989

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Ubiquitination of CXCR7 controls receptor trafficking AMD3100 is a potent antagonist at CXCR4(R334X) , a hyperfunctional mutant chemokine receptor and cause of WHIM syndrome Regulation of G protein-coupled receptors by allosteric ligands Endocytic trafficking of chemokine receptors Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina.Novel Structural Approaches to Study GPCR Regulation Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1 Novel roles for the E3 ubiquitin ligase atrophin-interacting protein 4 and signal transduction adaptor molecule 1 in G protein-coupled receptor signaling.The loss of RGS protein-Gα(i2) interactions results in markedly impaired mouse neutrophil trafficking to inflammatory sites.Neuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction.Regulation of C3a receptor signaling in human mast cells by G protein coupled receptor kinases.Quantitative phosphoproteomics unravels biased phosphorylation of serotonin 2A receptor at Ser280 by hallucinogenic versus nonhallucinogenic agonists.Dysplasia of Granulocytes in a Patient with HPV Disease, Recurrent Infections, and B Lymphopenia: A Novel Variant of WHIM Syndrome?Determination of sites of U50,488H-promoted phosphorylation of the mouse κ opioid receptor (KOPR): disconnect between KOPR phosphorylation and internalization An essential role of the cytoplasmic tail of CXCR4 in G-protein signaling and organogenesis.Using nanoBRET and CRISPR/Cas9 to monitor proximity to a genome-edited protein in real-time.Arrestin-2 interacts with the endosomal sorting complex required for transport machinery to modulate endosomal sorting of CXCR4 Loss of morphine reward and dependence in mice lacking G protein-coupled receptor kinase 5.HGF-induced PKCζ activation increases functional CXCR4 expression in human breast cancer cells.β-Arrestin1 and distinct CXCR4 structures are required for stromal derived factor-1 to downregulate CXCR4 cell-surface levels in neuroblastoma Constitutive phosphorylation by protein kinase C regulates D1 dopamine receptor signaling.Identification of phosphorylation sites in the COOH-terminal tail of the μ-opioid receptor Identification of the Rac-GEF P-Rex1 as an essential mediator of ErbB signaling in breast cancer.Identification and functional characterization of the phosphorylation sites of the neuropeptide FF2 receptor.Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code.Hierarchical organization of multi-site phosphorylation at the CXCR4 C terminus.Differential temporal and spatial regulation of somatostatin receptor phosphorylation and dephosphorylation.Baclofen and other GABAB receptor agents are allosteric modulators of the CXCL12 chemokine receptor CXCR4.Chemokine signaling in development and disease.Ligand-dependent mechanisms of sst2A receptor trafficking: role of site-specific phosphorylation and receptor activation in the actions of biased somatostatin agonists.Chemokine receptor Cxcr4 contributes to kidney fibrosis via multiple effectors.G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4 β-Arrestin-mediated receptor trafficking and signal transduction A broadly conserved g-protein-coupled receptor kinase phosphorylation mechanism controls Drosophila smoothened activity.IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis Role of myeloid-specific G-protein coupled receptor kinase-2 in sepsis.Suppression of G-protein-coupled receptor kinase 3 expression is a feature of classical GBM that is required for maximal growth.GRK2 protein-mediated transphosphorylation contributes to loss of function of μ-opioid receptors induced by neuropeptide FF (NPFF2) receptors.G Protein Coupled Receptor Kinase 3 Regulates Breast Cancer Migration, Invasion, and Metastasis.

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P2860

Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling.

http://www.wikidata.org/entity/Q30432989

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Site-specific phosphorylation ...... modulation of CXCR4 signaling.

@ast

Site-specific phosphorylation ...... modulation of CXCR4 signaling.

@en

type

label

Site-specific phosphorylation ...... modulation of CXCR4 signaling.

@ast

Site-specific phosphorylation ...... modulation of CXCR4 signaling.

@en

prefLabel

Site-specific phosphorylation ...... modulation of CXCR4 signaling.

@ast

Site-specific phosphorylation ...... modulation of CXCR4 signaling.

@en

P1433

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P356

JBC.M109.091173

P1433

Journal of Biological Chemistry

P1476

Site-specific phosphorylation ...... modulation of CXCR4 signaling.

@en

P2093

Jeffrey L Benovic

http://www.w3.org/2001/XMLSchema#string

John M Busillo

http://www.w3.org/2001/XMLSchema#string

Olimpia Meucci

http://www.w3.org/2001/XMLSchema#string

Rajarshi Sengupta

http://www.w3.org/2001/XMLSchema#string

Sylvain Armando

http://www.w3.org/2001/XMLSchema#string

P2860

Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization

beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4

The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4

The E3 ubiquitin ligase atrophin interacting protein 4 binds directly to the chemokine receptor CXCR4 via a novel WW domain-mediated interaction

A homozygous 1-base pair deletion in the arrestin gene is a frequent cause of Oguchi disease in Japanese

Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments

Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling

Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness

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7805-7817

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10.1074/JBC.M109.091173

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10

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285

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P577

2010-01-04T00:00:00Z

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20048153

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P921

phosphorylation

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2844224

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