HCN subunit-specific and cAMP-modulated effects of anesthetics on neuronal pacemaker currents.
about
HCN1 channel subunits are a molecular substrate for hypnotic actions of ketamine.Molecular targets underlying general anaesthesiaGeneral anesthesia mediated by effects on ion channelsPostnatal expression pattern of HCN channel isoforms in thalamic neurons: relationship to maturation of thalamocortical oscillations.HCN1 Channels Contribute to the Effects of Amnesia and Hypnosis but not Immobility of Volatile Anesthetics.Forebrain HCN1 channels contribute to hypnotic actions of ketamine.Local anesthetic inhibits hyperpolarization-activated cationic currents[What do we know about anesthetic mechanisms?: hypnosis, unresponsiveness to surgical incision and amnesia].Subunit-specific effects of isoflurane on neuronal Ih in HCN1 knockout mice.Suppression of ih contributes to propofol-induced inhibition of mouse cortical pyramidal neurons.HCN channels in behavior and neurological disease: too hyper or not active enough?Molecular mapping of general anesthetic sites in a voltage-gated ion channel.Nitric oxide activates hypoglossal motoneurons by cGMP-dependent inhibition of TASK channels and cGMP-independent activation of HCN channels.Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels.Mechanistic Insights into the Modulation of Voltage-Gated Ion Channels by Inhalational AnestheticsDistribution and intrinsic membrane properties of basal forebrain GABAergic and parvalbumin neurons in the mousePrefrontal cortex HCN1 channels enable intrinsic persistent neural firing and executive memory function.General anesthetics and molecular mechanisms of unconsciousnessShaker-related potassium channels in the central medial nucleus of the thalamus are important molecular targets for arousal suppression by volatile general anestheticsAlternatively spliced isoforms of TRIP8b differentially control h channel trafficking and function.Binding of the auxiliary subunit TRIP8b to HCN channels shifts the mode of action of cAMPExploring HCN channels as novel drug targets.HCN Channels Modulators: The Need for Selectivity.Differential regulation of HCN channel isoform expression in thalamic neurons of epileptic and non-epileptic rat strains.Novel role of KT5720 on regulating hyperpolarization-activated cyclic nucleotide-gated channel activity and dorsal root ganglion neuron excitability.Hyperpolarization-activated ion channels as targets for nitric oxide signalling in deep cerebellar nuclei.Dual stretch responses of mHCN2 pacemaker channels: accelerated activation, accelerated deactivation.Increased basal synaptic inhibition of hippocampal area CA1 pyramidal neurons by an antiepileptic drug that enhances I(H).Characteristics and physiological role of hyperpolarization activated currents in mouse cold thermoreceptors.The in vitro zebrafish heart as a model to investigate the chronotropic effects of vapor anesthetics.Plasticity of inwardly rectifying conductances following a corticospinal lesion in human subjects.Nitric oxide selectively suppresses IH currents mediated by HCN1-containing channels.Propofol inhibits HCN1 pacemaker channels by selective association with the closed states of the membrane embedded channel core.HCN channels contribute to the sensitivity of intravenous anesthetics in developmental mice.HCN Channels: New Therapeutic Targets for Pain Treatment
P2860
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P2860
HCN subunit-specific and cAMP-modulated effects of anesthetics on neuronal pacemaker currents.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
HCN subunit-specific and cAMP- ...... n neuronal pacemaker currents.
@ast
HCN subunit-specific and cAMP- ...... n neuronal pacemaker currents.
@en
type
label
HCN subunit-specific and cAMP- ...... n neuronal pacemaker currents.
@ast
HCN subunit-specific and cAMP- ...... n neuronal pacemaker currents.
@en
prefLabel
HCN subunit-specific and cAMP- ...... n neuronal pacemaker currents.
@ast
HCN subunit-specific and cAMP- ...... n neuronal pacemaker currents.
@en
P2093
P1476
HCN subunit-specific and cAMP- ...... on neuronal pacemaker currents
@en
P2093
Carl Lynch
Douglas A Bayliss
Edmund M Talley
Jay E Sirois
Xiangdong Chen
P304
P356
10.1523/JNEUROSCI.1153-05.2005
P407
P577
2005-06-01T00:00:00Z