A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics
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Activators of G protein signaling exhibit broad functionality and define a distinct core signaling triadPar1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytesStructural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein Subunit MutantsA P-loop Mutation in Gα Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal PathogenesisActivation of the regulator of G protein signaling 14-Gαi1-GDP signaling complex is regulated by resistance to inhibitors of cholinesterase-8ARole of layer 6 of V2 visual cortex in object-recognition memoryCell cycle-regulated membrane binding of NuMA contributes to efficient anaphase chromosome separation.LGN regulates mitotic spindle orientation during epithelial morphogenesis.Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cellsA structural determinant that renders G alpha(i) sensitive to activation by GIV/girdin is required to promote cell migration.Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82.Receptor-regulated interaction of activator of G-protein signaling-4 and Galphai.The hinge region of the scaffolding protein of cell contacts, zonula occludens protein 1, regulates interacting with various signaling proteins.Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor.Activators of G-protein signaling 3: a drug addiction molecular gateway.High-affinity immobilization of proteins using biotin- and GST-based coupling strategiesAGS-3 alters Caenorhabditis elegans behavior after food deprivation via RIC-8 activation of the neural G protein G αo.G protein-coupled receptors and resistance to inhibitors of cholinesterase-8A (Ric-8A) both regulate the regulator of g protein signaling 14 RGS14·Gαi1 complex in live cellsDirect Coupling of a Seven-Transmembrane-Span Receptor to a Gαi G-Protein Regulatory Motif Complex.Gαi3-Dependent Inhibition of JNK Activity on Intracellular Membranes.Regulation of the G-protein regulatory-Gαi signaling complex by nonreceptor guanine nucleotide exchange factors.Regulation of Airway Inflammation by G-protein Regulatory Motif Peptides of AGS3 protein.Translocation of activator of G-protein signaling 3 to the Golgi apparatus in response to receptor activation and its effect on the trans-Golgi network.Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif.GoLoco motif proteins binding to Galpha(i1): insights from molecular simulations.Ric-8A, an activator protein of Gαi, controls mammalian epithelial cell polarity for tight junction assembly and cystogenesis.Loss of the canonical spindle orientation function in the Pins/LGN homolog AGS3.Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein.
P2860
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P2860
A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A point mutation to Galphai se ...... es in mitotic spindle dynamics
@ast
A point mutation to Galphai se ...... es in mitotic spindle dynamics
@en
type
label
A point mutation to Galphai se ...... es in mitotic spindle dynamics
@ast
A point mutation to Galphai se ...... es in mitotic spindle dynamics
@en
prefLabel
A point mutation to Galphai se ...... es in mitotic spindle dynamics
@ast
A point mutation to Galphai se ...... es in mitotic spindle dynamics
@en
P2093
P2860
P50
P356
P1476
A point mutation to Galphai se ...... es in mitotic spindle dynamics
@en
P2093
Adam J Kimple
Christopher A Johnston
Dustin Bosch
Francis S Willard
Gregory J Digby
Jason M Conley
Melinda D Willard
Nevin A Lambert
Val J Watts
P2860
P304
36698-36710
P356
10.1074/JBC.M804936200
P407
P577
2008-11-04T00:00:00Z