Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore. - Wikidata - awgldk - TriplyDB

Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore.

Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore.

http://www.wikidata.org/entity/Q30437662

about

Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2 Hec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint control Linking kinetochore-microtubule binding to the spindle checkpoint ZW10 function in mitotic checkpoint control, dynein targeting and membrane trafficking: is dynein the unifying theme?Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components.Mechanism of Ska Recruitment by Ndc80 Complexes to Kinetochores.The distinct functions of CENP-C and CENP-T/W in centromere propagation and function in Xenopus egg extracts.Novel subcellular localization of the DNA helicase Twinkle at the kinetochore complex during mitosis in neuronal-like progenitor cells.CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status.Looping in on Ndc80 - how does a protein loop at the kinetochore control chromosome segregation?The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein.Aurora B kinase and protein phosphatase 1 have opposing roles in modulating kinetochore assembly.Direct physical study of kinetochore-microtubule interactions by reconstitution and interrogation with an optical force clamp.The human kinetochore proteins Nnf1R and Mcm21R are required for accurate chromosome segregation.Bod1, a novel kinetochore protein required for chromosome biorientation.The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusion.Multiple domains of human CLASP contribute to microtubule dynamics and organization in vitro and in Xenopus egg extracts.Contrasting models for kinetochore microtubule attachment in mammalian cells Vertebrate kinetochore protein architecture: protein copy number.The outer plate in vertebrate kinetochores is a flexible network with multiple microtubule interactions.The life and miracles of kinetochores.The MIS12 complex is a protein interaction hub for outer kinetochore assembly.Sos7, an essential component of the conserved Schizosaccharomyces pombe Ndc80-MIND-Spc7 complex, identifies a new family of fungal kinetochore proteins Point centromeres contain more than a single centromere-specific Cse4 (CENP-A) nucleosome.A mechanobiochemical mechanism for monooriented chromosome oscillation in mitosis.Minimal model for collective kinetochore-microtubule dynamics.The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spindle bipolarity Counting protein molecules using quantitative fluorescence microscopy.How to build a centromere: from centromeric and pericentromeric chromatin to kinetochore assembly.New insights into the mechanism for chromosome alignment in metaphase The Ndc80 complex: hub of kinetochore activity.Hec1 contributes to mitotic centrosomal microtubule growth for proper spindle assembly through interaction with Hice1.Bub1 targeting to centromeres is sufficient for Sgo1 recruitment in the absence of kinetochores.Anaphase A: Disassembling Microtubules Move Chromosomes toward Spindle Poles.Kinetochores' gripping feat: conformational wave or biased diffusion?Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes The conserved Spc7 protein is required for spindle integrity and links kinetochore complexes in fission yeast Cdt1 throws kinetochore-microtubule attachments for a loop.A Hec of a microtubule attachment.

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Measuring the stoichiometry and physical interactions between components elucidates the architecture of the vertebrate kinetochore.

http://www.wikidata.org/entity/Q30437662

description

2005 nî lūn-bûn

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2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2005 թվականի օգոստոսին հրատարակված գիտական հոդված

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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name

Measuring the stoichiometry an ...... of the vertebrate kinetochore.

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MBC.E05-03-0239

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Molecular Biology of the Cell

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Measuring the stoichiometry an ...... of the vertebrate kinetochore.

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P2093

David L Satinover

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Mark L McCleland

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Michael J Emanuele

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P2860

ZW10 links mitotic checkpoint signaling to the structural kinetochore.

A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension

The vertebrate Ndc80 complex contains Spc24 and Spc25 homologs, which are required to establish and maintain kinetochore-microtubule attachment

A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1

CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate

Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway

Hec1 and nuf2 are core components of the kinetochore outer plate essential for organizing microtubule attachment sites.

A new look at kinetochore structure in vertebrate somatic cells using high-pressure freezing and freeze substitution

hNuf2 inhibition blocks stable kinetochore-microtubule attachment and induces mitotic cell death in HeLa cells

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

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10.1091/MBC.E05-03-0239

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10

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16

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P Todd Stukenberg

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1237090

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