Epac signaling is required for hippocampus-dependent memory retrieval. - Wikidata - awgldk - TriplyDB

Epac signaling is required for hippocampus-dependent memory retrieval.

Epac signaling is required for hippocampus-dependent memory retrieval.

http://www.wikidata.org/entity/Q30440218

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Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).Redundant catecholamine signaling consolidates fear memory via phospholipase C.Epac2-mediated dendritic spine remodeling: implications for disease.Anxiety and depression with neurogenesis defects in exchange protein directly activated by cAMP 2-deficient mice are ameliorated by a selective serotonin reuptake inhibitor, Prozac.An association between Epac-1 gene variants and anxiety and depression in two independent samples Phosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair.Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection Prostanoid receptor EP2 as a therapeutic target Balanced dopamine is critical for pattern completion during associative memory recall.Activation of exchange protein activated by cAMP in the rat basolateral amygdala impairs reconsolidation of a memory associated with self-administered cocaine.The slow afterhyperpolarization: a target of β1-adrenergic signaling in hippocampus-dependent memory retrieval.Small G protein signaling in neuronal plasticity and memory formation: the specific role of ras family proteins Epac activation initiates associative odor preference memories in the rat pup.Inhibition of β-adrenergic receptors induces a persistent deficit in retrieval of a cocaine-associated memory providing protection against reinstatement Stress and glucocorticoids impair memory retrieval via β2-adrenergic, Gi/o-coupled suppression of cAMP signaling Neurofibromatosis-1 heterozygosity impairs CNS neuronal morphology in a cAMP/PKA/ROCK-dependent manner EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation.Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity.Structure-Activity Relationship Studies of Substituted 2-(Isoxazol-3-yl)-2-oxo-N'-phenyl-acetohydrazonoyl Cyanide Analogues: Identification of Potent Exchange Proteins Directly Activated by cAMP (EPAC) Antagonists.Epac Signaling Is Required for Cocaine-Induced Change in AMPA Receptor Subunit Composition in the Ventral Tegmental Area.NPY Y1 receptors differentially modulate GABAA and NMDA receptors via divergent signal-transduction pathways to reduce excitability of amygdala neurons.CaMKII, but not protein kinase A, regulates Rpt6 phosphorylation and proteasome activity during the formation of long-term memories.Exchange protein activated by cAMP enhances long-term memory formation independent of protein kinase A.Improvement of two-way active avoidance memory requires protein kinase a activation and brain-derived neurotrophic factor expression in the dorsal hippocampus EPAC proteins transduce diverse cellular actions of cAMP.The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.Role of Epac in brain and heart.A-kinase anchoring proteins: cAMP compartmentalization in neurodegenerative and obstructive pulmonary diseases.Neuromodulatory signaling in hippocampus-dependent memory retrieval.Xamoterol impairs hippocampus-dependent emotional memory retrieval via Gi/o-coupled β2-adrenergic signaling.A cell-based, quantitative and isoform-specific assay for exchange proteins directly activated by cAMP.The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons.Melatonin attenuates scopolamine-induced memory/synaptic disorder by rescuing EPACs/miR-124/Egr1 pathway.The Past, Present, and Future of Phosphodiesterase-4 Modulation for Age-Induced Memory Loss.Elevated aggressive behavior in male mice with thyroid-specific Prkar1a and global Epac1 gene deletion.8-pCPT, an Epac activator, impairs conditioned place preference based on nucleus accumbens amphetamine in rats.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.Epac2-deficiency leads to more severe retinal swelling, glial reactivity and oxidative stress in transient middle cerebral artery occlusion induced ischemic retinopathy.Prefrontal Neuronal Excitability Maintains Cocaine-Associated Memory During Retrieval.

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Epac signaling is required for hippocampus-dependent memory retrieval.

http://www.wikidata.org/entity/Q30440218

description

2008 nî lūn-bûn

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2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի օգոստոսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Epac signaling is required for hippocampus-dependent memory retrieval.

@ast

Epac signaling is required for hippocampus-dependent memory retrieval.

@en

type

label

Epac signaling is required for hippocampus-dependent memory retrieval.

@ast

Epac signaling is required for hippocampus-dependent memory retrieval.

@en

prefLabel

Epac signaling is required for hippocampus-dependent memory retrieval.

@ast

Epac signaling is required for hippocampus-dependent memory retrieval.

@en

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Epac signaling is required for hippocampus-dependent memory retrieval.

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P2093

Frank Schwede

http://www.w3.org/2001/XMLSchema#string

J Julius Zhu

http://www.w3.org/2001/XMLSchema#string

Lei Zhang

http://www.w3.org/2001/XMLSchema#string

Ming Ouyang

http://www.w3.org/2001/XMLSchema#string

Steven A Thomas

http://www.w3.org/2001/XMLSchema#string

P2860

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

A family of cAMP-binding proteins that directly activate Rap1

Central role of the CNGA4 channel subunit in Ca2+-calmodulin-dependent odor adaptation

Rolipram, a type IV-specific phosphodiesterase inhibitor, facilitates the establishment of long-lasting long-term potentiation and improves memory

A distinct role for norepinephrine in memory retrieval

Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP

Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase

The molecular biology of memory storage: a dialogue between genes and synapses

Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning

Modality-specific retrograde amnesia of fear

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