Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)
about
Identifying the rules of engagement enabling leukocyte rolling, activation, and adhesionMechanical switching and coupling between two dissociation pathways in a P-selectin adhesion bondDynamics of in silico leukocyte rolling, activation, and adhesion.Catch bonds govern adhesion through L-selectin at threshold shearImprovements to parallel plate flow chambers to reduce reagent and cellular requirementsIntraoperative intravital microscopy permits the study of human tumour vesselsForce and torque on spherical particles in micro-channel flows using computational fluid dynamics2015 Clinical trials update in sickle cell anemiaAn activated L-selectin mutant with conserved equilibrium binding properties but enhanced ligand recognition under shear flowRegulation of catch bonds by rate of force applicationFunctional analysis of the combined role of the O-linked branching enzyme core 2 beta1-6-N-glucosaminyltransferase and dimerization of P-selectin glycoprotein ligand-1 in rolling on P-selectinGlycosyltransferase-programmed stereosubstitution (GPS) to create HCELL: engineering a roadmap for cell migrationNonlinear flow affects hydrodynamic forces and neutrophil adhesion rates in cone-plate viscometers.Probing dynamic cell-substrate interactions using photochemically generated surface-immobilized gradients: application to selectin-mediated leukocyte rollingRegulation of L-selectin-dependent hydrodynamic shear thresholding by leukocyte deformability and shear dependent bond number.A direct comparison of selectin-mediated transient, adhesive events using high temporal resolution.Comparison of PSGL-1 microbead and neutrophil rolling: microvillus elongation stabilizes P-selectin bond clusters.Autoperfused mouse flow chamber reveals synergistic neutrophil accumulation through P-selectin and E-selectin.Oxidized low-density lipoprotein contributes to atherogenesis via co-activation of macrophages and mast cellsL-selectin shear thresholding modulates leukocyte secondary capture.Microparticle adhesive dynamics and rolling mediated by selectin-specific antibodies under flow.Molecular stiffness of selectins.The Effects of Load on E-Selectin Bond Rupture and Bond Formation.Event-tracking model of adhesion identifies load-bearing bonds in rolling leukocytes.Nano-motion dynamics are determined by surface-tethered selectin mechanokinetics and bond formation.Agent-based model of therapeutic adipose-derived stromal cell trafficking during ischemia predicts ability to roll on P-selectin.Enhancement of L-selectin, but not P-selectin, bond formation frequency by convective flow.Direct observation of membrane tethers formed during neutrophil attachment to platelets or P-selectin under physiological flow.Measuring molecular elasticity by atomic force microscope cantilever fluctuations.Neutrophil string formation: hydrodynamic thresholding and cellular deformation during cell collisions.Targeted delivery of therapeutics to endothelium.Biomechanics of P-selectin PSGL-1 bonds: shear threshold and integrin-independent cell adhesionL-selectin-mediated lymphocyte-cancer cell interactions under low fluid shear conditionsTransmission of allostery through the lectin domain in selectin-mediated cell adhesion.Selectin catch-slip kinetics encode shear threshold adhesive behavior of rolling leukocytesExamining the lateral displacement of HL60 cells rolling on asymmetric P-selectin patternsNeutrophil rolling at high shear: flattening, catch bond behavior, tethers and slingsSoluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity.Plug flow cytometry extends analytical capabilities in cell adhesion and receptor pharmacology.Visualization of allostery in P-selectin lectin domain using MD simulations.
P2860
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P2860
Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)
description
1997 nî lūn-bûn
@nan
1997 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)
@ast
Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)
@en
type
label
Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)
@ast
Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)
@en
prefLabel
Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)
@ast
Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)
@en
P2093
P2860
P356
P1476
Threshold levels of fluid shear promote leukocyte adhesion through selectins (CD62L,P,E)
@en
P2093
P2860
P304
P356
10.1083/JCB.136.3.717
P407
P577
1997-02-01T00:00:00Z