Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments. - Wikidata - awgldk - TriplyDB

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments.

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments.

http://www.wikidata.org/entity/Q30442799

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Mitochondria, cholesterol and cancer cell metabolism Targeting mitochondria metabolism for cancer therapy A small molecule with anticancer and antimetastatic activities induces rapid mitochondrial-associated necrosis in breast cancer.ROS homeostasis and metabolism: a dangerous liason in cancer cells Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth Using semi-quantitative dynamic contrast-enhanced magnetic resonance imaging parameters to evaluate tumor hypoxia: a preclinical feasibility study in a maxillofacial VX2 rabbit model Selective Vulnerability of Cancer Cells by Inhibition of Ca(2+) Transfer from Endoplasmic Reticulum to Mitochondria Mitochondrial DNA somatic mutation in cancer Enriched environment inhibits mouse pancreatic cancer growth and down-regulates the expression of mitochondria-related genes in cancer cells.Mitophagy and cancer.Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors Prognostic Significance of Transverse Relaxation Rate (R2*) in Blood Oxygenation Level-Dependent Magnetic Resonance Imaging in Patients with Invasive Breast Cancer.Withania somnifera Root Extract Enhances Chemotherapy through 'Priming'.Aberrantly upregulated TRAP1 is required for tumorigenesis of breast cancer.Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells TP53 mutation, mitochondria and cancer.A novel agent exerts antitumor activity in breast cancer cells by targeting mitochondrial complex II Iron chelators target both proliferating and quiescent cancer cells.Mechanistic review of drug-induced steatohepatitis Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.Systematic identification of genes involved in metabolic acid stress resistance in yeast and their potential as cancer targets.Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1-Dependent Apoptosis in Cancer Cells Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.Ibuprofen Induces Mitochondrial-Mediated Apoptosis Through Proteasomal Dysfunction.Extracellular iron diminishes anticancer effects of vitamin C: an in vitro study.VDAC-Tubulin, an Anti-Warburg Pro-Oxidant Switch.A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.Flat cells come full sphere: Are mutant cytoskeletal-related proteins oncoprotein-monsters or useful immunogens?Tumor acidosis enhances cytotoxic effects and autophagy inhibition by salinomycin on cancer cell lines and cancer stem cells The secret life of quiescent cancer stem cells Targeting mitochondrial translation by inhibiting DDX3: a novel radiosensitization strategy for cancer treatment.Bliss and Loewe interaction analyses of clinically relevant drug combinations in human colon cancer cell lines reveal complex patterns of synergy and antagonism.Cytotoxicity of portoamides in human cancer cells and analysis of the molecular mechanisms of action.Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development.MYC is downregulated by a mitochondrial checkpoint mechanism.Targeting Metabolism for Cancer Therapy.Mitochondrial Inhibition Augments the Efficacy of Imatinib by Resetting the Metabolic Phenotype of Gastrointestinal Stromal Tumor.MitoQ regulates autophagy by inducing a pseudo-mitochondrial membrane potential.Design, synthesis, cytotoxicity evaluation and docking studies of 1,2,4-triazine derivatives bearing different arylidene-hydrazinyl moieties as potential mTOR inhibitors.

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P2860

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments.

http://www.wikidata.org/entity/Q30442799

description

2014 nî lūn-bûn

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2014 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2014 թվականի հունվարին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Induction of mitochondrial dys ...... compromised microenvironments.

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Induction of mitochondrial dys ...... compromised microenvironments.

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Induction of mitochondrial dys ...... compromised microenvironments.

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Induction of mitochondrial dys ...... compromised microenvironments.

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Induction of mitochondrial dys ...... compromised microenvironments.

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Angelo De Milito

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Emma Hernlund

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Joachim Gullbo

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Leoni A Kunz Schughart

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Linda Rickardson

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Long Dang

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Maria Hägg Olofsson

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Mårten Fryknäs

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Padraig D'Arcy

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Sven Påhlman

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P2860

BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

TOR signaling in growth and metabolism

Exploiting tumour hypoxia in cancer treatment

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Hypoxia--a key regulatory factor in tumour growth

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain

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10.1038/NCOMMS4295

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24548894

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3929804

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