Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.
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Metformin is associated with survival benefit in pancreatic cancer patients with diabetes: a systematic review and meta-analysis.Pyridine Dinucleotides from Molecules to Man.Exploiting ROS and metabolic differences to kill cisplatin resistant lung cancer.Understanding the Intersections between Metabolism and Cancer Biology.Mitochondria-targeted metformins: anti-tumour and redox signalling mechanisms.Regulation of organelle function by metformin.Biochemical Underpinnings of Immune Cell Metabolic Phenotypes.The Mitochondrial Complex(I)ty of Cancer.Cytosolic malate dehydrogenase activity helps support glycolysis in actively proliferating cells and cancerThe ABC7 regimen: a new approach to metastatic breast cancer using seven common drugs to inhibit epithelial-to-mesenchymal transition and augment capecitabine efficacy.N-Acetylaspartate Metabolism Outside the Brain: Lipogenesis, Histone Acetylation, and Cancer.Metabolic coupling and the Reverse Warburg Effect in cancer: Implications for novel biomarker and anticancer agent development.Targeting Metabolism for Cancer Therapy.Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells.Mitochondrial Metabolism: Yin and Yang for Tumor Progression.Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain-dependent manner.Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect.The effects of metformin on gut microbiota and the immune system as research frontiers.Impact of diabetes mellitus on the risk and survival of nasopharyngeal carcinoma: a meta-analysis.A Randomized Phase II Study of Metformin plus Paclitaxel/Carboplatin/Bevacizumab in Patients with Chemotherapy-Naïve Advanced or Metastatic Nonsquamous Non-Small Cell Lung Cancer.The Oncojanus Paradigm of Respiratory Complex I.Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response.Actionable Metabolic Pathways in Heart Failure and Cancer—Lessons From Cancer Cell Metabolism.Aspartate is an endogenous metabolic limitation for tumour growthPotential Mechanisms Connecting Purine Metabolism and Cancer TherapyFR58P1a; a new uncoupler of OXPHOS that inhibits migration in triple-negative breast cancer cells via Sirt1/AMPK/β1-integrin pathwayMicroenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies
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P2860
Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Environment Dictates Dependenc ...... Cell Sensitivity to Metformin.
@en
type
label
Environment Dictates Dependenc ...... Cell Sensitivity to Metformin.
@en
prefLabel
Environment Dictates Dependenc ...... Cell Sensitivity to Metformin.
@en
P2093
P2860
P50
P1433
P1476
Environment Dictates Dependenc ...... Cell Sensitivity to Metformin.
@en
P2093
Aaron M Hosios
Elizaveta Freinkman
Lauren N Bush
Matthew G Vander Heiden
Nadege Gitego
Shawn M Davidson
P2860
P304
P356
10.1016/J.CMET.2016.09.006
P577
2016-10-13T00:00:00Z