Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma - Wikidata - awgldk - TriplyDB

Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma

Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma

http://www.wikidata.org/entity/Q30443359

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Pancreatic cancer stem cell markers and exosomes - the incentive push Epithelial to mesenchymal transition of a primary prostate cell line with switches of cell adhesion modules but without malignant transformation.Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development Epithelial-mesenchymal transitions and hepatocarcinogenesis.Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells Production of antibodies with peptide-CpG-DNA-liposome complex without carriers.Correlations between transmembrane 4 L6 family member 5 (TM4SF5), CD151, and CD63 in liver fibrotic phenotypes and hepatic migration and invasive capacities Cross talk between the TM4SF5/focal adhesion kinase and the interleukin-6/STAT3 pathways promotes immune escape of human liver cancer cells.Therapeutic effect of a TM4SF5-specific peptide vaccine against colon cancer in a mouse model Prevention and therapy of hepatocellular carcinoma by vaccination with TM4SF5 epitope-CpG-DNA-liposome complex without carriers Glucosamine treatment-mediated O-GlcNAc modification of paxillin depends on adhesion state of rat insulinoma INS-1 cells.TM4SF5-mediated protein-protein networks and tumorigenic roles.Therapeutic effect of a TM4SF5-specific monoclonal antibody against colon cancer in a mouse model.TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1.Interaction of tetraspan(in) TM4SF5 with CD44 promotes self-renewal and circulating capacities of hepatocarcinoma cells.TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo.Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity.Production of epitope-specific antibodies using peptide-CpG-ODN-liposome complex without carriers and their application as a cancer vaccine in mice.Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein.A HLA-A2-restricted CTL epitope induces anti-tumor effects against human lung cancer in mouse xenograft model TM4SF1 Promotes Proliferation, Invasion, and Metastasis in Human Liver Cancer Cells Epithelial-mesenchymal transition in hepatocellular carcinoma.Anti-metastatic effect of the TM4SF5-specific peptide vaccine and humanized monoclonal antibody on colon cancer in a mouse lung metastasis model.Differential regulation of cellular functions by the C-termini of transmembrane 4 L six family proteins in 2- or 3-dimensional environment.Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5.TM4SF5-Mediated Roles in the Development of Fibrotic Phenotypes Recent progress in therapeutic applications of chalcones.Biomarkers for hepatocellular carcinoma: diagnostic and therapeutic utility.Loss of E-cadherin expression is not a prerequisite for c-erbB2-induced epithelial-mesenchymal transition.A high level of TM4SF5 is associated with human esophageal cancer progression and poor patient survival.Adenovirus-mediated delivery of siRNA targeting TM4SF4 attenuated liver cancer cell growth in vitro and in vivo.Cross-talk between TGFβ1 and EGFR signalling pathways induces TM4SF5 expression and epithelial-mesenchymal transition.Human tetraspanin transmembrane 4 superfamily member 4 or intestinal and liver tetraspan membrane protein is overexpressed in hepatocellular carcinoma and accelerates tumor cell growth.Antagonistic regulation of transmembrane 4 L6 family member 5 attenuates fibrotic phenotypes in CCl(4) -treated mice.The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration.Proteasome inhibition causes epithelial-mesenchymal transition upon TM4SF5 expression.A novel protein associated with membrane-type 1 matrix metalloproteinase binds p27(kip1) and regulates RhoA activation, actin remodeling, and matrigel invasion.Blockade of four-transmembrane L6 family member 5 (TM4SF5)-mediated tumorigenicity in hepatocytes by a synthetic chalcone derivative.Tetraspanin in oncogenic epithelial-mesenchymal transition.TMPRSS4 induces invasion and epithelial-mesenchymal transition through upregulation of integrin alpha5 and its signaling pathways.

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Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma

http://www.wikidata.org/entity/Q30443359

description

2008 nî lūn-bûn

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2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2008 թվականի ապրիլին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Tetraspanin TM4SF5 mediates lo ...... ition in human hepatocarcinoma

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Tetraspanin TM4SF5 mediates lo ...... ition in human hepatocarcinoma

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Tetraspanin TM4SF5 mediates lo ...... ition in human hepatocarcinoma

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Tetraspanin TM4SF5 mediates lo ...... ition in human hepatocarcinoma

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Tetraspanin TM4SF5 mediates lo ...... ition in human hepatocarcinoma

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Tetraspanin TM4SF5 mediates lo ...... ition in human hepatocarcinoma

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Eun-Sil Kang

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Ik-Hyun Cho

http://www.w3.org/2001/XMLSchema#string

In-San Kim

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Ju-Ock Nam

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Jung Weon Lee

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Ki Hun Park

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Mimi Tamamori-Adachi

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Min-A Oh

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Sang-Kyu Ye

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Semi Kim

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P2860

A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.

Identification of a new tumour-associated antigen TM4SF5 and its expression in human cancer

14-3-3 suppresses the nuclear localization of threonine 157-phosphorylated p27(Kip1)

Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

The L6 membrane proteins--a new four-transmembrane superfamily

The integrin-actin connection, an eternal love affair

Epithelial-mesenchymal transitions in tumour progression

Integrins: bidirectional, allosteric signaling machines

CDK inhibitors: positive and negative regulators of G1-phase progression

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

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1354-1366

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10.1172/JCI33768

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4

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118

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18357344

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2268877

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