Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration
about
Linked production of pyroglutamate-modified proteins via self-cleavage of fusion tags with TEV protease and autonomous N-terminal cyclization with glutaminyl cyclase in vivoAn anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 miceLocus-specific epigenetic remodeling controls addiction- and depression-related behaviors.Comparative pathobiology of β-amyloid and the unique susceptibility of humans to Alzheimer's diseaseDistinct spatiotemporal accumulation of N-truncated and full-length amyloid-β42 in Alzheimer's disease.Amyloid-beta (Aβ₁₋₄₂)-induced paralysis in Caenorhabditis elegans is inhibited by the polyphenol quercetin through activation of protein degradation pathways.
P2860
Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Glutaminyl cyclase-mediated to ...... ces striatal neurodegeneration
@ast
Glutaminyl cyclase-mediated to ...... ces striatal neurodegeneration
@en
type
label
Glutaminyl cyclase-mediated to ...... ces striatal neurodegeneration
@ast
Glutaminyl cyclase-mediated to ...... ces striatal neurodegeneration
@en
prefLabel
Glutaminyl cyclase-mediated to ...... ces striatal neurodegeneration
@ast
Glutaminyl cyclase-mediated to ...... ces striatal neurodegeneration
@en
P2093
P2860
P50
P356
P1433
P1476
Glutaminyl cyclase-mediated to ...... ces striatal neurodegeneration
@en
P2093
Anca Alexandru
Andreas Becker
Christoph Bäuscher
Hans-Ulrich Demuth
Reinhard Sedlmeier
Sigrid Graubner
Stephan Schilling
Stephanie Kohlmann
Wolfgang Jagla
P2860
P2888
P356
10.1186/1471-2202-14-108
P577
2013-10-01T00:00:00Z
P5875
P6179
1029092848