Drosophila TGIF proteins are transcriptional activators.
about
An autoinhibitory effect of the homothorax domain of Meis2Tgif1 and Tgif2 regulate Nodal signaling and are required for gastrulation.The Tgif2 gene contains a retained intron within the coding sequence.Premature senescence and increased TGFβ signaling in the absence of Tgif1.dSno facilitates baboon signaling in the Drosophila brain by switching the affinity of Medea away from Mad and toward dSmad2.Tgif1 and Tgif2 Repress Expression of the RabGAP Evi5l.Genetic and Molecular Analyses indicate independent effects of TGIFs on Nodal and Gli3 in neural tube patterning.Tgif1 and Tgif2 Regulate Axial Patterning in Mouse.Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.Targeted disruption of Tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice.Differential roles of TGIF family genes in mammalian reproduction.BmTGIF, a Bombyx mori homolog of Drosophila DmTGIF, regulates progression of spermatogenesis.Lmo7 is an emerin-binding protein that regulates the transcription of emerin and many other muscle-relevant genes.Use with caution: developmental systems divergence and potential pitfalls of animal models.BmAly is an important factor in meiotic progression and spermatid differentiation in Bombyx mori (Lepidoptera: Bombycidae).Zebrafish model of holoprosencephaly demonstrates a key role for TGIF in regulating retinoic acid metabolism.Functions of TGIF homeodomain proteins and their roles in normal brain development and holoprosencephaly
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P2860
Drosophila TGIF proteins are transcriptional activators.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Drosophila TGIF proteins are transcriptional activators.
@ast
Drosophila TGIF proteins are transcriptional activators.
@en
type
label
Drosophila TGIF proteins are transcriptional activators.
@ast
Drosophila TGIF proteins are transcriptional activators.
@en
prefLabel
Drosophila TGIF proteins are transcriptional activators.
@ast
Drosophila TGIF proteins are transcriptional activators.
@en
P2860
P1476
Drosophila TGIF proteins are transcriptional activators.
@en
P2093
Cathy A Hyman
Stuart J Newfeld
P2860
P304
P356
10.1128/MCB.23.24.9262-9274.2003
P407
P577
2003-12-01T00:00:00Z