Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation
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Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsp190RhoGAP is cell cycle regulated and affects cytokinesis.Role of p120 Ras-GAP in directed cell movementInflammatory breast cancer: relationship between growth factor signaling and motility in aggressive cancersPTP-PEST couples membrane protrusion and tail retraction via VAV2 and p190RhoGAP.Arhgap28 is a RhoGAP that inactivates RhoA and downregulates stress fibersCharacterization of a brain-specific Rho GTPase-activating protein, p200RhoGAPE-cadherin negatively regulates neoplastic growth in non-small cell lung cancer: role of Rho GTPasesSpatiotemporal regulation of Src and its substrates at invadosomesFunctional cross-talk between ras and rho pathways: a Ras-specific GTPase-activating protein (p120RasGAP) competitively inhibits the RhoGAP activity of deleted in liver cancer (DLC) tumor suppressor by masking the catalytic arginine fingerDeciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS.Signaling pathways that control rho kinase activity maintain the embryonic epicardial progenitor state.Phosphorylation of the p190 RhoGAP N-terminal domain by c-Src results in a loss of GTP binding activity.Cancer-associated mutations in the protrusion-targeting region of p190RhoGAP impact tumor cell migration.The human papillomavirus E7 proteins associate with p190RhoGAP and alter its function.Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability.Mitotic down-regulation of p190RhoGAP is required for the successful completion of cytokinesisExtracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP.Localized suppression of RhoA activity by Tyr31/118-phosphorylated paxillin in cell adhesion and migration.Adenovirus E4 open reading frame 4-induced apoptosis involves dysregulation of Src family kinases.Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane.p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line.Role of protein tyrosine phosphatase SHP2 in barrier function of pulmonary endothelium.Extracellular signal-regulated kinase 1 interacts with and phosphorylates CdGAP at an important regulatory siteRhoA inactivation by p190RhoGAP regulates cell spreading and migration by promoting membrane protrusion and polarity.Characterization of a novel GTPase-activating protein associated with focal adhesions and the actin cytoskeleton.The human orthologue of CdGAP is a phosphoprotein and a GTPase-activating protein for Cdc42 and Rac1 but not RhoA.β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells.Rho-regulatory proteins in breast cancer cell motility and invasion.P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells.Regulation of adherens junction dynamics by phosphorylation switches.Mutant K-RAS Promotes Invasion and Metastasis in Pancreatic Cancer Through GTPase Signaling Pathways.Src family kinases differentially influence glioma growth and motilityRho/RacGAPs: embarras de richesse?Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective.Current knowledge of the large RhoGAP family of proteins.p190RhoGAP is the convergence point of adhesion signals from alpha 5 beta 1 integrin and syndecan-4.RhoA is down-regulated at cell-cell contacts via p190RhoGAP-B in response to tensional homeostasis.Protein tyrosine phosphatases: structure-function relationships.RasGAPs: a crucial regulator of extracellular stimuli for homeostasis of cellular functions.
P2860
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P2860
Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Phosphotyrosine (p-Tyr)-depend ...... mediator of complex formation
@ast
Phosphotyrosine (p-Tyr)-depend ...... mediator of complex formation
@en
type
label
Phosphotyrosine (p-Tyr)-depend ...... mediator of complex formation
@ast
Phosphotyrosine (p-Tyr)-depend ...... mediator of complex formation
@en
prefLabel
Phosphotyrosine (p-Tyr)-depend ...... mediator of complex formation
@ast
Phosphotyrosine (p-Tyr)-depend ...... mediator of complex formation
@en
P2093
P2860
P356
P1476
Phosphotyrosine (p-Tyr)-depend ...... mediator of complex formation
@en
P2093
M D Haskell
S J Parsons
P2860
P304
P356
10.1128/MCB.18.12.7052
P407
P577
1998-12-01T00:00:00Z