Inhibition of telomerase recruitment and cancer cell death
about
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapiesGenetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulationCauses of genome instability: the effect of low dose chemical exposures in modern societyIdentification of human TERT elements necessary for telomerase recruitment to telomeres.Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase.Hoyeraal-Hreidarsson syndrome caused by a germline mutation in the TEL patch of the telomere protein TPP1.A novel somatic mutation in ACD induces telomere lengthening and apoptosis resistance in leukemia cellsCancer-associated TERT promoter mutations abrogate telomerase silencingDownregulation of telomerase maintenance-related ACD expression in patients undergoing immunosuppresive therapy following kidney transplantationNEK6-mediated phosphorylation of human TPP1 regulates telomere length through telomerase recruitment.Control of telomerase action at human telomeresStructural and functional consequences of a disease mutation in the telomere protein TPP1.Short-term inhibition of TERT induces telomere length-independent cell cycle arrest and apoptotic response in EBV-immortalized and transformed B cells.A lentivirus-free inducible CRISPR-Cas9 system for efficient targeting of human genes.Omacetaxine mepesuccinate induces apoptosis and cell cycle arrest, promotes cell differentiation, and reduces telomerase activity in diffuse large B‑cell lymphoma cells.Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cellsThe N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action.Shwachman-Diamond Syndrome Protein SBDS Maintains Human Telomeres by Regulating Telomerase Recruitment.
P2860
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P2860
Inhibition of telomerase recruitment and cancer cell death
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Inhibition of telomerase recruitment and cancer cell death
@ast
Inhibition of telomerase recruitment and cancer cell death
@en
type
label
Inhibition of telomerase recruitment and cancer cell death
@ast
Inhibition of telomerase recruitment and cancer cell death
@en
prefLabel
Inhibition of telomerase recruitment and cancer cell death
@ast
Inhibition of telomerase recruitment and cancer cell death
@en
P2860
P50
P356
P1476
Inhibition of telomerase recruitment and cancer cell death
@en
P2093
Joaquín M Espinosa
Mai Nakashima
P2860
P304
33171-33180
P356
10.1074/JBC.M113.518175
P407
P577
2013-10-04T00:00:00Z