Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses
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BDNF deregulation in Rett syndromeA review of Rett syndrome (RTT) with induced pluripotent stem cellsRett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressorFoxO6 regulates memory consolidation and synaptic functionMeCP2 deficiency results in robust Rett-like behavioural and motor deficits in male and female ratsSensory processing in autism spectrum disorders and Fragile X syndrome-From the clinic to animal models.Loss of MeCP2 in the rat models regression, impaired sociability and transcriptional deficits of Rett syndrome.Degraded neural and behavioral processing of speech sounds in a rat model of Rett syndrome.Automatic cortical representation of auditory pitch changes in Rett syndrome.Characterization of Rett Syndrome-like phenotypes in Mecp2-knockout ratsInduced gamma oscillations differentiate familiar and novel voices in children with MECP2 duplication and Rett syndromes.Cellular origins of auditory event-related potential deficits in Rett syndromeBeyond Widespread Mecp2 Deletions to Model Rett Syndrome: Conditional Spatio-Temporal Knockout, Single-Point Mutations and Transgenic Rescue MicePreclinical research in Rett syndrome: setting the foundation for translational success.Mice with an isoform-ablating Mecp2 exon 1 mutation recapitulate the neurologic deficits of Rett syndrome.Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.Development of a Novel AAV Gene Therapy Cassette with Improved Safety Features and Efficacy in a Mouse Model of Rett SyndromeImproved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery.The Crucial Role of DNA Methylation and MeCP2 in Neuronal FunctionOxidative brain damage in Mecp2-mutant murine models of Rett syndromeThe neural circuit basis of Rett syndromeRespiratory phenotypes are distinctly affected in mice with common Rett syndrome mutations MeCP2 T158A and R168X.Overview of mouse models of autism spectrum disordersGestational hypoxia and epigenetic programming of brain development disorders.Characterization of the MeCP2R168X knockin mouse model for Rett syndrome.Rett syndrome like phenotypes in the R255X Mecp2 mutant mouse are rescued by MECP2 transgeneCircadian cycle-dependent MeCP2 and brain chromatin changesGenotype-specific effects of Mecp2 loss-of-function on morphology of Layer V pyramidal neurons in heterozygous female Rett syndrome model mice.The methyl-CpG-binding domain (MBD) is crucial for MeCP2's dysfunction-induced defects in adult newborn neuronsPhysics-Based Potentials for Coarse-Grained Modeling of Protein-DNA InteractionsRett syndrome: genes, synapses, circuits, and therapeuticsMeCP2 Related Studies Benefit from the Use of CD1 as Genetic Background.MicroRNAs downregulated in neuropathic pain regulate MeCP2 and BDNF related to pain sensitivity.Characterization of spatio-temporal epidural event-related potentials for mouse models of psychiatric disorders.Phosphorylation of MeCP2 at Ser421 contributes to chronic antidepressant action.The relationship of Rett syndrome and MECP2 disorders to autism.Loss of CDKL5 disrupts kinome profile and event-related potentials leading to autistic-like phenotypes in mice.The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndromeMeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome.Epigenetic mechanisms in neurological disease
P2860
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P2860
Rett syndrome mutation MeCP2 T158A disrupts DNA binding, protein stability and ERP responses
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Rett syndrome mutation MeCP2 T ...... in stability and ERP responses
@ast
Rett syndrome mutation MeCP2 T ...... in stability and ERP responses
@en
type
label
Rett syndrome mutation MeCP2 T ...... in stability and ERP responses
@ast
Rett syndrome mutation MeCP2 T ...... in stability and ERP responses
@en
prefLabel
Rett syndrome mutation MeCP2 T ...... in stability and ERP responses
@ast
Rett syndrome mutation MeCP2 T ...... in stability and ERP responses
@en
P2093
P2860
P356
P1433
P1476
Rett syndrome mutation MeCP2 T ...... in stability and ERP responses
@en
P2093
Amy Mercado-Berton
Arith-Ruth S Reyes
Caroline Ong
Gregory C Carlson
I-Ting Judy Wang
Julie A Blendy
Maria Amorim
Megan Allen
P2860
P2888
P304
P356
10.1038/NN.2997
P407
P577
2011-11-27T00:00:00Z