Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity - Wikidata - awgldk - TriplyDB

Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity

Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity

http://www.wikidata.org/entity/Q30476276

about

A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo Insulin-modulated Akt subcellular localization determines Akt isoform-specific signaling.T-REX on-demand redox targeting in live cells.Self-organization of intracellular gradients during mitosis.Akt-PDK1 complex mediates epidermal growth factor-induced membrane protrusion through Ral activation.Optical molecular imaging for systems biology: from molecule to organism.Identification of sites within a monomeric red fluorescent protein that tolerate peptide insertion and testing of corresponding circular permutations.Dystrophin glycoprotein complex-associated Gbetagamma subunits activate phosphatidylinositol-3-kinase/Akt signaling in skeletal muscle in a laminin-dependent manner.Thymosin-β4 (Tβ4) blunts PDGF-dependent phosphorylation and binding of AKT to actin in hepatic stellate cells.Genetically encodable fluorescent biosensors for tracking signaling dynamics in living cells.Protein kinase A activity at the endoplasmic reticulum surface is responsible for augmentation of human ether-a-go-go-related gene product (HERG).Visualization of cellular phosphoinositide pools with GFP-fused protein-domains Visualizing dynamic activities of signaling enzymes using genetically encodable FRET-based biosensors from designs to applications.Molecular mechanisms regulating the hormone sensitivity of breast cancer.Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma.PTEN lipid phosphatase activity and proper subcellular localization are necessary and sufficient for down-regulating AKT phosphorylation in the nucleus in Cowden syndrome.Moving toward the light: using new technology to answer old questions Multiplexed visualization of dynamic signaling networks using genetically encoded fluorescent protein-based biosensors Spatiotemporal analysis of differential Akt regulation in plasma membrane microdomains Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration.Live cell imaging of phosphoinositides with expressed inositide binding protein domains Akt signaling dynamics in plasma membrane microdomains visualized by FRET-based reporters.Spatiotemporal dynamics of phosphorylation in lipid second messenger signaling.Green light to illuminate signal transduction events.Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics.3-D structure and dynamics of protein kinase B-new mechanism for the allosteric regulation of an AGC kinase.Vitamin E facilitates the inactivation of the kinase Akt by the phosphatase PHLPP1.The Akt kinases: isoform specificity in metabolism and cancer.Exploring cells with targeted biosensors FRET and mechanobiology Modeling of spatially-restricted intracellular signaling.The chemical biology of phosphoinositide 3-kinases.Genetically encoded fluorescent biosensors for live-cell visualization of protein phosphorylation.Nuclear transport: a switch for the oxidative stress-signaling circuit?Parallel tracking of cAMP and PKA signaling dynamics in living cells with FRET-based fluorescent biosensors.Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells.Live-cell imaging of cell signaling using genetically encoded fluorescent reporters.AKT-mediated regulation of polarization in differentiated human neutrophil-like HL-60 cells.Spatiotemporal Dynamics of Kinase Signaling Visualized by Targeted Reporters.The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of

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Signal propagation from membrane messengers to nuclear effectors revealed by reporters of phosphoinositide dynamics and Akt activity

http://www.wikidata.org/entity/Q30476276

description

2005 nî lūn-bûn

@nan

2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Signal propagation from membra ...... tide dynamics and Akt activity

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Signal propagation from membra ...... tide dynamics and Akt activity

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type

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Signal propagation from membra ...... tide dynamics and Akt activity

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Signal propagation from membra ...... tide dynamics and Akt activity

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Signal propagation from membra ...... tide dynamics and Akt activity

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Signal propagation from membra ...... tide dynamics and Akt activity

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PNAS.0502889102

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Signal propagation from membra ...... tide dynamics and Akt activity

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P2093

Bharath Ananthanarayanan

http://www.w3.org/2001/XMLSchema#string

Jin Zhang

http://www.w3.org/2001/XMLSchema#string

Qiang Ni

http://www.w3.org/2001/XMLSchema#string

P2860

A transmembrane intracellular estrogen receptor mediates rapid cell signaling

The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex

A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C

Reducing the environmental sensitivity of yellow fluorescent protein. Mechanism and applications

High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate

PTEN and myotubularin: novel phosphoinositide phosphatases.

The Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cells

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

Role of translocation in the activation and function of protein kinase B

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

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15081-15086

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scholarly article

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10.1073/PNAS.0502889102

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42

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102

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