Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion. - Wikidata - awgldk - TriplyDB

Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion.

Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion.

http://www.wikidata.org/entity/Q30480137

about

Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1 Autosomal dominant polycystic kidney disease: the last 3 years Role of the Polycystins in Cell Migration, Polarity, and Tissue Morphogenesis A polycystin-centric view of cyst formation and disease: the polycystins revisited Physiological mechanisms and therapeutic potential of bone mechanosensing.Crawling cells can close wounds without purse strings or signaling Pkd1 regulates lymphatic vascular morphogenesis during development Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells.Polycystin-1 regulates actin cytoskeleton organization and directional cell migration through a novel PC1-Pacsin 2-N-Wasp complex.Regulation of the microtubular cytoskeleton by Polycystin-1 favors focal adhesions turnover to modulate cell adhesion and migration.A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus.Conditional disruption of Pkd1 in osteoblasts results in osteopenia due to direct impairment of bone formation.Cyclic mechanical stretch decreases cell migration by inhibiting phosphatidylinositol 3-kinase- and focal adhesion kinase-mediated JNK1 activation.Polycystin-1 protein level determines activity of the Galpha12/JNK apoptosis pathway.Modulation of the secretory pathway rescues zebrafish polycystic kidney disease pathology.Plasma membrane ion fluxes and NFAT-dependent gene transcription contribute to c-met-induced epithelial scattering.Fibroin and sericin from Bombyx mori silk stimulate cell migration through upregulation and phosphorylation of c-Jun.Renal-retinal ciliopathy gene Sdccag8 regulates DNA damage response signaling Aberrant regulation of planar cell polarity in polycystic kidney disease Cilium, centrosome and cell cycle regulation in polycystic kidney disease.Fibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD).Selective dicer suppression in the kidney alters GSK3β/β-catenin pathways promoting a glomerulocystic disease.Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling.Histone acetyltransferase inhibitor C646 reverses epithelial to mesenchymal transition of human peritoneal mesothelial cells via blocking TGF-β1/Smad3 signaling pathway in vitro VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis The polycystic kidney disease 1 (Pkd1) gene is required for the responses of osteochondroprogenitor cells to midpalatal suture expansion in mice.Glis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.Pkd1 is required for male reproductive tract development Characterization of primary cilia in human airway smooth muscle cells.Emerging evidence of a link between the polycystins and the mTOR pathways.Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.Calcium-mediated mechanisms of cystic expansion.Molecular genetics and pathogenic mechanisms for the severe ciliopathies: insights into neurodevelopment and pathogenesis of neural tube defects.Mammalian target of rapamycin and the kidney. II. Pathophysiology and therapeutic implications.Polycystins and cellular Ca2+ signaling.Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling The hallmarks of cancer: relevance to the pathogenesis of polycystic kidney disease.Role of apoptosis in the development of autosomal dominant polycystic kidney disease (ADPKD).Control of cell mechanics by RhoA and calcium fluxes during epithelial scattering.Selenium suppresses lipopolysaccharide-induced fibrosis in peritoneal mesothelial cells through inhibition of epithelial-to-mesenchymal transition.

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Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion.

http://www.wikidata.org/entity/Q30480137

description

2007 nî lūn-bûn

@nan

2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի օգոստոսին հրատարակված գիտական հոդված

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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name

Polycystin-1 induces cell migr ...... cell cell mechanical adhesion.

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Polycystin-1 induces cell migr ...... cell cell mechanical adhesion.

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type

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Polycystin-1 induces cell migr ...... cell cell mechanical adhesion.

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Polycystin-1 induces cell migr ...... cell cell mechanical adhesion.

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Polycystin-1 induces cell migr ...... cell cell mechanical adhesion.

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MBC.E07-02-0142

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Molecular Biology of the Cell

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Polycystin-1 induces cell migr ...... cell cell mechanical adhesion.

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P2093

Alessandra Boletta

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Gianfranco Distefano

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Gregory G Germino

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Lisa D'Amato

http://www.w3.org/2001/XMLSchema#string

Manila Boca

http://www.w3.org/2001/XMLSchema#string

Roman S Polishchuk

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P2860

Polycystin-1 and polycystin-2 regulate the cell cycle through the helix-loop-helix inhibitor Id2

PKD1 interacts with PKD2 through a probable coiled-coil domain

Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.

The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

Axin directly interacts with plakoglobin and regulates its stability

Role of polycystins in renal tubulogenesis

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli

Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

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10.1091/MBC.E07-02-0142

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10

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18

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2007-08-01T00:00:00Z

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17671167

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1995705

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