Examining the link between chromosomal instability and aneuploidy in human cells - Wikidata - awgldk - TriplyDB

Examining the link between chromosomal instability and aneuploidy in human cells

Examining the link between chromosomal instability and aneuploidy in human cells

http://www.wikidata.org/entity/Q30481428

about

ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4 The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells Loss of pRB causes centromere dysfunction and chromosomal instability Genome stability is ensured by temporal control of kinetochore-microtubule dynamics Aneuploidy: cancer's fatal flaw?Chromosomal instability and cancer: a complex relationship with therapeutic potential Towards a quantitative understanding of mitotic spindle assembly and mechanics The role of aneuploidy in promoting and suppressing tumors Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate Aneuploidy: cells losing their balance When 2+2=5: the origins and fates of aneuploid and tetraploid cells Thirty years of search and capture: The complex simplicity of mitotic spindle assembly Centrosomes, chromosome instability (CIN) and aneuploidy Regulation of kinetochore-microtubule attachments through homeostatic control during mitosis Aurora B hyperactivation by Bub1 overexpression promotes chromosome missegregation Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes Basic mechanism for biorientation of mitotic chromosomes is provided by the kinetochore geometry and indiscriminate turnover of kinetochore microtubules.Cellular and Molecular Features of Developmentally Programmed Genome Rearrangement in a Vertebrate (Sea Lamprey: Petromyzon marinus)Quantitative assessment of chromosome instability induced through chemical disruption of mitotic progression Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells Novel functions for the endocytic regulatory proteins MICAL-L1 and EHD1 in mitosis.Elevated tolerance to aneuploidy in cancer cells: estimating the fitness effects of chromosome number alterations by in silico modelling of somatic genome evolution BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1 A screen for selective killing of cells with chromosomal instability induced by a spindle checkpoint defect The causes and consequences of genetic heterogeneity in cancer evolution A mechanism linking extra centrosomes to chromosomal instability The mitotic origin of chromosomal instability.Mechanisms of chromosome behaviour during mitosis Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis.Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure.High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells.Up-regulation of the mitotic checkpoint component Mad1 causes chromosomal instability and resistance to microtubule poisons Cell cycle-dependent localization of CHK2 at centrosomes during mitosis.Loss of centrioles causes chromosomal instability in vertebrate somatic cells.Whole chromosome gain does not in itself confer cancer-like chromosomal instability Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation.TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation.

P2860

Q24297488-EC510DF2-B1D0-4C77-8A22-F85A7F6973E4 Q24305557-16F11299-5023-46DF-91E3-997873D10D3C Q24321598-428148C6-3E4C-40EC-AF2D-627083E14E0C Q24322655-D292ADD5-8B16-444A-AF13-64E2D014109C Q24595815-7D527A80-E9C1-42E4-8101-FFAD742636FA Q24608609-BD790A12-CEB5-4569-BDAF-60ABB8AA546A Q24633928-87764C1E-7B04-4092-8622-F4D8FF38CE89 Q24648182-412E6385-108D-4780-A59F-3EB8CF9E5D7C Q24648997-28976D7C-8714-4865-816A-ED9E3154E64A Q24654413-B4671D81-5368-467C-B769-5A3A1B5CD28D Q24658364-09BDE5F2-CA8F-40D1-BBF2-488DAAF3E582 Q26775862-AC14B3BB-E71C-4736-8BF7-6353866A77D5 Q26865035-A29D53D2-B10C-4DF0-83BD-D6447BD09C01 Q26866233-098FCE99-1499-46A2-BD5A-C26D2E93F0DF Q26995347-9E9FA989-D359-4128-AB6F-55B38095392E Q27301063-F49E4428-C536-421E-BD76-45934BF5101E Q27305370-EF6B4DE1-4633-4634-A3EB-85019D09160B Q27308765-ACED2BF7-116F-42E7-8507-F52A74A409F8 Q27311350-C8FF3BBE-F822-43CE-8E62-DA6879F696D8 Q27319918-67F1C706-2798-4AB1-A7CF-A0A640198D6F Q27336129-43A29653-78BC-4247-96E7-204E1EA1FFE0 Q27345177-12BB4E1F-6BFF-462C-AD7A-0F5564D1E37E Q27346737-D683CD86-C8D8-44A1-94C0-6BD3CBEC6840 Q28386176-0D549F1A-BAD7-480C-9BBE-E0AFC42F1303 Q28468367-7230510A-1DE2-4907-A329-55A3255A76C5 Q28477755-397B4E28-3758-4FBB-B5C7-1155E85A71FB Q28484384-93E061B9-2041-44AF-8686-2D09635CEC27 Q29615848-7582FBA4-4FC5-4EC7-BEB5-B57A96A0E561 Q29617923-9439B137-2039-4484-A065-08CC35FEEF06 Q30408039-E5540A2B-E589-4274-B46D-C953FA20A953 Q30495185-AD3C4A60-12F0-4426-AEA7-C9C8EEA46C99 Q30496764-FC99A7B0-310F-4BD0-8251-235580D325A1 Q30498092-977EA781-7529-469C-9191-FA91F7A21BB6 Q30499296-09F2FD98-CD43-42A4-A164-657567E62BFF Q30524222-784BE37E-DD65-4E6C-AD42-C140F681D033 Q30540177-AE67A63C-2D24-47F6-9FE7-698BA4B1E06C Q30559126-044DD377-9CCA-4FFD-AD4C-6A4E898F5768 Q30560979-7F9F7AE6-5995-4A8B-A13C-046FC64E325F Q30579157-2042E299-E6CF-4089-8D78-328A882C7538 Q30580516-A0DB3BD3-A643-4513-9244-A1A3A4AA988A

P2860

Examining the link between chromosomal instability and aneuploidy in human cells

http://www.wikidata.org/entity/Q30481428

description

2008 nî lūn-bûn

@nan

2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Examining the link between chromosomal instability and aneuploidy in human cells

@ast

Examining the link between chromosomal instability and aneuploidy in human cells

@en

type

label

Examining the link between chromosomal instability and aneuploidy in human cells

@ast

Examining the link between chromosomal instability and aneuploidy in human cells

@en

prefLabel

Examining the link between chromosomal instability and aneuploidy in human cells

@ast

Examining the link between chromosomal instability and aneuploidy in human cells

@en

P1433

Q30481428-159051ED-CA23-4F0E-928C-AD1FC90159D5

P1476

Q30481428-235B29B6-4F6F-4321-9945-36948CD47788

P2093

Q30481428-9596493F-BD26-419F-B2D3-FC444F0047D8

Q30481428-FFDC2E69-B0F4-4B93-9BC4-A4AE96838B1B

P2860

Q30481428-0429D3B3-1868-46A8-8B14-1AF4B41D3A13

Q30481428-18C81299-1694-4FC1-AF79-E0494D519E95

Q30481428-1C1E0C19-A6E1-45D4-8C08-34F91A52F49E

Q30481428-1FCB8D20-A00B-479C-A8C3-361CBFDAD784

Q30481428-26D1FCDE-3428-499B-B897-49A6A1992465

Q30481428-30930160-949C-46DD-A470-079AC0B86E76

Q30481428-350985C1-D6F3-4A75-AFB3-34A62067D8DA

Q30481428-4488B688-52EB-40A6-A938-0F01AD53DABD

Q30481428-48882784-8760-4BE2-8DF3-53EE1BE0FDE1

Q30481428-4D637A19-92CA-41BC-8946-3425563B4E6C

P304

Q30481428-EBF32671-33E8-4486-AB78-7744D25B6EE9

P31

Q30481428-5943FAB0-8919-413C-8B9D-854839BC99C0

P356

Q30481428-5CC03497-A90E-4C47-8AF4-32F605E2BBFE

P407

Q30481428-12AF3773-494B-42F0-9865-5954B360ECC2

P433

Q30481428-A3B9F9ED-901A-412E-A84B-FF91BD0AF58D

P478

Q30481428-429BC0E6-E54D-488D-887E-F78C9E31AD55

P577

Q30481428-D5897389-45D9-49D8-9E95-DC82A7DAC030

P5875

Q30481428-F06F5139-792F-4AD7-B0A2-E3F4A4845678

P698

Q30481428-C30ECBDC-93C5-4201-A40F-6E16C0900614

P932

Q30481428-2ECBCE0C-39A6-4EE0-BB89-87C819DEA793

P356

P1433

Journal of Cell Biology

P1476

Examining the link between chromosomal instability and aneuploidy in human cells

@en

P2093

Duane A Compton

http://www.w3.org/2001/XMLSchema#string

Sarah L Thompson

http://www.w3.org/2001/XMLSchema#string

P2860

Tripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachments

Mutations of mitotic checkpoint genes in human cancers

Centrosome amplification drives chromosomal instability in breast tumor development.

The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint

Genetic instabilities in human cancers

Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments

From polyploidy to aneuploidy, genome instability and cancer

The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly

Efficient mitosis in human cells lacking poleward microtubule flux

Aneuploid colon cancer cells have a robust spindle checkpoint

P304

665-672

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1083/JCB.200712029

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

180

http://www.w3.org/2001/XMLSchema#string

P577

2008-02-18T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5569325

http://www.w3.org/2001/XMLSchema#string

P698

18283116

http://www.w3.org/2001/XMLSchema#string

P932

2265570

http://www.w3.org/2001/XMLSchema#string