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Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

http://www.wikidata.org/entity/Q30488694

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The synaptic pathology of alpha-synuclein aggregation in dementia with Lewy bodies, Parkinson's disease and Parkinson's disease dementia Brain organochlorines and Lewy pathology: the Honolulu-Asia aging study Molecular Pathological Classification of Neurodegenerative Diseases: Turning towards Precision Medicine Gut Feelings About α-Synuclein in Gastrointestinal Biopsies: Biomarker in the Making?Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies.Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease Clinicopathological outcomes of prospectively followed normal elderly brain bank volunteers.Urban air pollution: influences on olfactory function and pathology in exposed children and young adults.The transgenic overexpression of alpha-synuclein and not its related pathology associates with complex I inhibition.Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders.Prevalence of Submandibular Gland Synucleinopathy in Parkinson's Disease, Dementia with Lewy Bodies and other Lewy Body Disorders Critical role of truncated α-synuclein and aggregates in Parkinson's disease and incidental Lewy body disease.BACE1 levels by APOE genotype in non-demented and Alzheimer's post-mortem brains Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic study Abnormal neurites containing C-terminally truncated alpha-synuclein are present in Alzheimer's disease without conventional Lewy body pathology.Evaluation of subcortical pathology and clinical correlations in FTLD-U subtypes.National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease Air pollution is associated with brainstem auditory nuclei pathology and delayed brainstem auditory evoked potentials.Cell type specific sequestration of choline acetyltransferase and tyrosine hydroxylase within Lewy bodies.Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene Alpha-synuclein in peripheral tissues and body fluids as a biomarker for Parkinson's disease - a systematic review.Frequency of Alzheimer's disease pathology at autopsy in patients with clinical normal pressure hydrocephalus.Biochemical increase in phosphorylated alpha-synuclein precedes histopathology of Lewy-type synucleinopathies A guide to neurotoxic animal models of Parkinson's disease National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach.Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment Alpha-Synuclein Pathology in Sensory Nerve Terminals of the Upper Aerodigestive Tract of Parkinson's Disease Patients Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons Feasibility Study: Comparison of Frontal Cortex Needle Core Versus Open Biopsy for Detection of Characteristic Proteinopathies of Neurodegenerative Diseases Incidental Lewy body disease: do some cases represent a preclinical stage of dementia with Lewy bodies?Phosphorylated α-synuclein-immunoreactive retinal neuronal elements in Parkinson's disease subjects.Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program.Parkinson's disease is not associated with gastrointestinal myenteric ganglion neuron loss.Synchrotron FTIR micro-spectroscopy for structural analysis of Lewy bodies in the brain of Parkinson's disease patients.Mitochondrial targeting sequence variants of the CHCHD2 gene are a risk for Lewy body disorders Alpha-synuclein pathology and axonal degeneration of the peripheral motor nerves innervating pharyngeal muscles in Parkinson disease Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings Submandibular gland biopsy for the diagnosis of Parkinson disease Corticospinal tract degeneration associated with TDP-43 type C pathology and semantic dementia Lewy pathology is not the first sign of degeneration in vulnerable neurons in Parkinson disease.

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P2860

Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

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Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

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Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

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Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

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Acta Neuropathologica

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Christa L Hladik

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Federico Roncaroli

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John E Duda

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Joseph V Noorigian

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Lucia I Sue

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Manuel Buttini

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Ronald L Hamilton

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Takeshi Iwatsubo

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P2860

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

Alpha-synuclein in Lewy bodies

Prominent perikaryal expression of alpha- and beta-synuclein in neurons of dorsal root ganglion and in medullary neurons

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred.

Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders

Alpha-synuclein in Lewy body disease and Alzheimer's disease.

Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry.

alpha-Synuclein is phosphorylated in synucleinopathy lesions.

Demonstration of alpha-synuclein immunoreactivity in neuronal and glial cytoplasm in normal human brain tissue using proteinase K and formic acid pretreatment.

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Dennis W. Dickson

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Charles L White

Charles H Adler

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immunohistochemistry

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