Biochemical increase in phosphorylated alpha-synuclein precedes histopathology of Lewy-type synucleinopathies
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c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's diseaseReduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's diseaseMolecular Pathological Classification of Neurodegenerative Diseases: Turning towards Precision MedicineAlpha-synuclein biology in Lewy body diseasesNeuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation.Parkinson's disease-implicated kinases in the brain; insights into disease pathogenesis.Prevalence of Submandibular Gland Synucleinopathy in Parkinson's Disease, Dementia with Lewy Bodies and other Lewy Body DisordersQuantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry.rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration.Evaluating the relationship between amyloid-β and α-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson's disease.SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening.TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal CorticesArizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program.Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein.Submandibular gland biopsy for the diagnosis of Parkinson diseaseChanges in properties of serine 129 phosphorylated α-synuclein with progression of Lewy-type histopathology in human brains.Cortical phosphorylated α-Synuclein levels correlate with brain wave spectra in Parkinson's diseaseActivation of tyrosine kinase c-Abl contributes to α-synuclein-induced neurodegenerationThe pathomechanisms underlying Parkinson's disease.Review: Spreading the word: precise animal models and validated methods are vital when evaluating prion-like behaviour of alpha-synuclein.Sensitive western blotting for detection of endogenous Ser129-phosphorylated α-synuclein in intracellular and extracellular spacesTenuigenin attenuates α-synuclein-induced cytotoxicity by down-regulating polo-like kinase 3.Altered ceramide acyl chain length and ceramide synthase gene expression in Parkinson’s disease.Prion-Like Seeding of Misfolded α-Synuclein in the Brains of Dementia with Lewy Body Patients in RT-QUIC.Lysosomal-associated membrane protein 2 isoforms are differentially affected in early Parkinson's disease.c-Abl and Parkinson's Disease: Mechanisms and Therapeutic Potential.Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not α-synuclein pathology.
P2860
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P2860
Biochemical increase in phosphorylated alpha-synuclein precedes histopathology of Lewy-type synucleinopathies
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2012 nî lūn-bûn
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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2012年论文
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2012年论文
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name
Biochemical increase in phosph ...... of Lewy-type synucleinopathies
@ast
Biochemical increase in phosph ...... of Lewy-type synucleinopathies
@en
type
label
Biochemical increase in phosph ...... of Lewy-type synucleinopathies
@ast
Biochemical increase in phosph ...... of Lewy-type synucleinopathies
@en
prefLabel
Biochemical increase in phosph ...... of Lewy-type synucleinopathies
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Biochemical increase in phosph ...... of Lewy-type synucleinopathies
@en
P2093
P2860
P1433
P1476
Biochemical increase in phosph ...... of Lewy-type synucleinopathies
@en
P2093
Douglas G Walker
Haruhiko Akiyama
Holly Shill
John Caviness
Lih-Fen Lue
Lucia I Sue
Marwan N Sabbagh
P2860
P304
P356
10.1111/J.1750-3639.2012.00585.X
P577
2012-04-12T00:00:00Z