Temporal and mutation-specific alterations in Ca2+ homeostasis differentially determine the progression of cTnT-related cardiomyopathies in murine models.
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Cell biology of sarcomeric protein engineering: disease modeling and therapeutic potentialThin filament mutations: developing an integrative approach to a complex disorderDPP4 deficiency preserved cardiac function in abdominal aortic banding ratsSexually dimorphic myofilament function and cardiac troponin I phosphospecies distribution in hypertrophic cardiomyopathy miceA Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function.Influence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytesHypertrophic cardiomyopathy: a heart in need of an energy bar?Investigating the role of uncoupling of troponin I phosphorylation from changes in myofibrillar Ca(2+)-sensitivity in the pathogenesis of cardiomyopathy.Genetics of hypertrophic cardiomyopathy.Synthetic phosphopeptides enable quantitation of the content and function of the four phosphorylation states of phospholamban in cardiac muscleCardiac myosin heavy chain isoform exchange alters the phenotype of cTnT-related cardiomyopathies in mouse hearts.Diltiazem treatment for pre-clinical hypertrophic cardiomyopathy sarcomere mutation carriers: a pilot randomized trial to modify disease expression.Phospholamban phosphorylation, mutation, and structural dynamics: a biophysical approach to understanding and treating cardiomyopathy.Cardiac myosin binding protein-C: redefining its structure and function.Atomic resolution probe for allostery in the regulatory thin filament.Subtle abnormalities in contractile function are an early manifestation of sarcomere mutations in dilated cardiomyopathy.Functionally conservative substitutions at cardiac troponin I S43/45.Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation.HCM-linked ∆160E cardiac troponin T mutation causes unique progressive structural and molecular ventricular remodeling in transgenic mice.Delineation of Molecular Pathways Involved in Cardiomyopathies Caused by Troponin T MutationsHypertrophic cardiomyopathy: how do mutations lead to disease?Experimental models of inherited cardiomyopathy and its therapeutics.Cardiac troponin structure-function and the influence of hypertrophic cardiomyopathy associated mutations on modulation of contractility.Peroxisome proliferator-activated receptor-α expression induces alterations in cardiac myofilaments in a pressure-overload model of hypertrophy.A One Health Approach to Hypertrophic Cardiomyopathy.Familial hypertrophic cardiomyopathy: functional variance among individual cardiomyocytes as a trigger of FHC-phenotype development.Accurate quantitation of phospholamban phosphorylation by immunoblot.The Role of Calcium/Calmodulin-Dependent Protein Kinase II Activation in Hypertrophic Cardiomyopathy.The structural basis of alpha-tropomyosin linked (Asp230Asn) familial dilated cardiomyopathy.Genotype-Dependent and -Independent Calcium Signaling Dysregulation in Human Hypertrophic Cardiomyopathy.Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models.The genetics of hypertrophic cardiomyopathy
P2860
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P2860
Temporal and mutation-specific alterations in Ca2+ homeostasis differentially determine the progression of cTnT-related cardiomyopathies in murine models.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Temporal and mutation-specific ...... iomyopathies in murine models.
@ast
Temporal and mutation-specific ...... iomyopathies in murine models.
@en
type
label
Temporal and mutation-specific ...... iomyopathies in murine models.
@ast
Temporal and mutation-specific ...... iomyopathies in murine models.
@en
prefLabel
Temporal and mutation-specific ...... iomyopathies in murine models.
@ast
Temporal and mutation-specific ...... iomyopathies in murine models.
@en
P2093
P2860
P1476
Temporal and mutation-specific ...... iomyopathies in murine models.
@en
P2093
Candice C Dowell-Martino
Jil C Tardiff
Nathaniel Sibinga
Pia J Guinto
Todd E Haim
P2860
P304
P356
10.1152/AJPHEART.01143.2008
P577
2009-06-05T00:00:00Z