Phosphoinositide-dependent protein kinase (PDK) activity regulates phosphatidylinositol 3,4,5-trisphosphate-dependent and -independent protein kinase B activation and chemotaxis
about
Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesPerspectives in PDK1 evolution: insights from photosynthetic and non-photosynthetic organismsGlycogen synthase kinase-3 is required for efficient Dictyostelium chemotaxis.Disruption of PKB signaling restores polarity to cells lacking tumor suppressor PTEN.Delineating the core regulatory elements crucial for directed cell migration by examining folic-acid-mediated responsesMoving in the right direction: how eukaryotic cells migrate along chemical gradients.Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis.TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing.Signaling network from GPCR to the actin cytoskeleton during chemotaxis.PP2A/B56 and GSK3/Ras suppress PKB activity during Dictyostelium chemotaxis.Daydreamer, a Ras effector and GSK-3 substrate, is important for directional sensing and cell motilityRegulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling PathwayChemoattractant stimulation of TORC2 is regulated by receptor/G protein-targeted inhibitory mechanisms that function upstream and independently of an essential GEF/Ras activation pathway in Dictyostelium.Signaling mechanisms for chemotaxis.A PIP5 kinase essential for efficient chemotactic signaling.Analysis of chemotaxis in Dictyostelium.Protein kinase B gene homologue pkbR1 performs one of its roles at first finger stage of Dictyostelium.Dual TORCs driven and B56 orchestrated signaling network guides eukaryotic cell migration.Chemotaxis: new role for Ras revealed.Protein kinase A regulates the Ras, Rap1 and TORC2 pathways in response to the chemoattractant cAMP in Dictyostelium.Migration of Dictyostelium discoideum to the Chemoattractant Folic Acid.
P2860
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P2860
Phosphoinositide-dependent protein kinase (PDK) activity regulates phosphatidylinositol 3,4,5-trisphosphate-dependent and -independent protein kinase B activation and chemotaxis
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Phosphoinositide-dependent pro ...... se B activation and chemotaxis
@ast
Phosphoinositide-dependent pro ...... se B activation and chemotaxis
@en
type
label
Phosphoinositide-dependent pro ...... se B activation and chemotaxis
@ast
Phosphoinositide-dependent pro ...... se B activation and chemotaxis
@en
prefLabel
Phosphoinositide-dependent pro ...... se B activation and chemotaxis
@ast
Phosphoinositide-dependent pro ...... se B activation and chemotaxis
@en
P2860
P356
P1476
Phosphoinositide-dependent pro ...... se B activation and chemotaxis
@en
P2093
Peter N Devreotes
Yoichiro Kamimura
P2860
P304
P356
10.1074/JBC.M109.089235
P407
P577
2010-01-14T00:00:00Z