Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
about
Migration of Th1 lymphocytes is regulated by CD152 (CTLA-4)-mediated signaling via PI3 kinase-dependent Akt activationThe lipid phosphatase activity of PTEN is critical for its tumor supressor functionRequirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytesControl of glycogen synthesis in cultured human muscle cellsFyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinaseStructural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85alpha Src homology 2 domains with phosphoinositides and inositol polyphosphatesDAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositidesCharacterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinaseDifferential regulation of the phosphatidylinositol 3-kinase/Akt and p70 S6 kinase pathways by the alpha(1A)-adrenergic receptor in rat-1 fibroblastsA phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cellsClass II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptorsMolecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinasesThe kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation siteRegulation of the Akt/Glycogen synthase kinase-3 axis by insulin-like growth factor-II via activation of the human insulin receptor isoform-AThe interaction of Akt with APPL1 is required for insulin-stimulated Glut4 translocationSystematic Analysis Reveals Elongation Factor 2 and α-Enolase as Novel Interaction Partners of AKT2Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent mannerPyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesionsThe tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells.Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 functionRegulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/AktKinetic mechanism of AKT/PKB enzyme familySilencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signaling to the actin cytoskeletonFurther evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complexDAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosisClipR-59 interacts with Akt and regulates Akt cellular compartmentalizationAssociation of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulinC2 domain-containing phosphoprotein CDP138 regulates GLUT4 insertion into the plasma membrane.3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signalingInhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrateActivation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alphaRole of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivoThe PI3K-PDK1 connection: more than just a road to PKBPhosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinaseSignal-dependent membrane targeting by pleckstrin homology (PH) domainsPlatelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt
P2860
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P2860
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
description
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1997
@ast
im April 1997 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1997/04/01)
@sk
vědecký článek publikovaný v roce 1997
@cs
wetenschappelijk artikel (gepubliceerd op 1997/04/01)
@nl
наукова стаття, опублікована у квітні 1997
@uk
مقالة علمية (نشرت في أبريل 1997)
@ar
name
Characterization of a 3-phosph ...... ctivates protein kinase Balpha
@ast
Characterization of a 3-phosph ...... ctivates protein kinase Balpha
@en
Characterization of a 3-phosph ...... ctivates protein kinase Balpha
@nl
type
label
Characterization of a 3-phosph ...... ctivates protein kinase Balpha
@ast
Characterization of a 3-phosph ...... ctivates protein kinase Balpha
@en
Characterization of a 3-phosph ...... ctivates protein kinase Balpha
@nl
prefLabel
Characterization of a 3-phosph ...... ctivates protein kinase Balpha
@ast
Characterization of a 3-phosph ...... ctivates protein kinase Balpha
@en
Characterization of a 3-phosph ...... ctivates protein kinase Balpha
@nl
P2093
P3181
P1433
P1476
Characterization of a 3-phosph ...... ctivates protein kinase Balpha
@en
P2093
A. B. Holmes
C. B. Reese
C. P. Downes
D. R. Alessi
P. R. Gaffney
S. R. James
P304
P3181
P356
10.1016/S0960-9822(06)00122-9
P407
P577
1997-04-01T00:00:00Z