Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning. - Wikidata - awgldk - TriplyDB

Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning.

Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning.

http://www.wikidata.org/entity/Q30494493

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Glutamatergic targets for new alcohol medications Stress-induced deficits in cognition and emotionality: a role of glutamate Major Histocompatibility Complex class I proteins are critical for maintaining neuronal structural complexity in the aging brain Surface expression of hippocampal NMDA GluN2B receptors regulated by fear conditioning determines its contribution to memory consolidation in adult rats.Effects of a Flavonoid-Rich Fraction on the Acquisition and Extinction of Fear Memory: Pharmacological and Molecular Approaches.Basic roles of key molecules connected with NMDAR signaling pathway on regulating learning and memory and synaptic plasticity A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.p120-catenin is necessary for neuroprotection induced by CDK5 silencing in models of Alzheimer's disease Neuralized1 activates CPEB3: a function for nonproteolytic ubiquitin in synaptic plasticity and memory storage Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder Effects of genetic deletion of the Kv4.2 voltage-gated potassium channel on murine anxiety-, fear- and stress-related behaviors.Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype.GluN2B in corticostriatal circuits governs choice learning and choice shifting.The nucleosome assembly protein TSPYL2 regulates the expression of NMDA receptor subunits GluN2A and GluN2B.Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior Exome Sequence Data From Multigenerational Families Implicate AMPA Receptor Trafficking in Neurocognitive Impairment and Schizophrenia Risk.Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults.Identification of postsynaptic phosphatidylinositol-4,5-bisphosphate (PIP2) roles for synaptic plasticity using chemically induced dimerization NMDA receptor-dependent LTD is required for consolidation but not acquisition of fear memory.Hippocampal long-term depression is required for the consolidation of spatial memory.NR2B-deficient mice are more sensitive to the locomotor stimulant and depressant effects of ethanol Loss of GluN2A-containing NMDA receptors impairs extra-dimensional set-shifting Life extension factor klotho enhances cognition.GluN2B protein deficits in the left, but not the right, hippocampus in schizophrenia.Effects of PI3Kγ overexpression in the hippocampus on synaptic plasticity and spatial learning.Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice.NMDA receptor subunits in the adult rat hippocampus undergo similar changes after 5 minutes in an open field and after LTP induction.Behavioral and synaptic circuit features in a zebrafish model of fragile X syndrome.GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner.Prenatal ethanol exposure impairs executive function in mice into adulthood.SynGAP regulates protein synthesis and homeostatic synaptic plasticity in developing cortical networks.Moderate prenatal alcohol exposure enhances GluN2B containing NMDA receptor binding and ifenprodil sensitivity in rat agranular insular cortex Contributions of β2 subunit-containing nAChRs to chronic nicotine-induced alterations in cognitive flexibility in mice.Prenatal inhibition of the kynurenine pathway leads to structural changes in the hippocampus of adult rat offspring.Deletion of the NMDA receptor GluN2A subunit significantly decreases dendritic growth in maturing dentate granule neurons Conditional loss of GluN2B in cortex and hippocampus impairs attentional set formation.Impaired discrimination learning in interneuronal NMDAR-GluN2B mutant mice

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P2860

Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning.

http://www.wikidata.org/entity/Q30494493

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Loss of GluN2B-containing NMDA ...... ensity, and disrupts learning.

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Loss of GluN2B-containing NMDA ...... ensity, and disrupts learning.

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type

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Loss of GluN2B-containing NMDA ...... ensity, and disrupts learning.

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Loss of GluN2B-containing NMDA ...... ensity, and disrupts learning.

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Loss of GluN2B-containing NMDA ...... ensity, and disrupts learning.

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Loss of GluN2B-containing NMDA ...... ensity, and disrupts learning.

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JNEUROSCI.0640-10.2010

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Loss of GluN2B-containing NMDA ...... ensity, and disrupts learning.

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Andrew Holmes

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David M Lovinger

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Eric Delpire

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Gail K Seabold

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Giuseppe Talani

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Jonathan L Brigman

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Shweta Prasad-Mulcare

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Genetic enhancement of learning and memory in mice

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Subregion- and cell type-restricted gene knockout in mouse brain

The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory

Cyclin-dependent kinase 5 governs learning and synaptic plasticity via control of NMDAR degradation

Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice

Increased thresholds for long-term potentiation and contextual learning in mice lacking the NMDA-type glutamate receptor epsilon1 subunit

NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses

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4590-4600

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Margaret I. Davis

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