Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis. - Wikidata - awgldk - TriplyDB

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

http://www.wikidata.org/entity/Q30494581

about

G protein-coupled receptors participate in cytokinesis Non-muscle myosin II in disease: mechanisms and therapeutic opportunities Approaches of targeting Rho GTPases in cancer drug discovery Pathway as a pharmacological target for herbal medicines: an investigation from reduning injection An inverse small molecule screen to design a chemically defined medium supporting long-term growth of Drosophila cell lines Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development.Small molecule probes of cellular pathways and networks.Postgenomic technologies targeting the Wnt signaling network.RNAi screening: new approaches, understandings, and organisms.Generation of stable Drosophila cell lines using multicistronic vectors.The why and how of phenotypic small-molecule screens.Target identification and mechanism of action in chemical biology and drug discovery.Targeting Rho-GTPases in immune cell migration and inflammation.Anti-obesity phenotypic screening looking to increase OBR cell surface expression.Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery.Apolipoprotein E Inhibits Cerebrovascular Pericyte Mobility through a RhoA Protein-mediated Pathway.Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes.Myosin light chains: Teaching old dogs new tricks Innovation in academic chemical screening: filling the gaps in chemical biology Bactrocera dorsalis male sterilization by targeted RNA interference of spermatogenesis: empowering sterile insect technique programs.Comparative interaction networks: bridging genotype to phenotype.Luciferase reporter assay in Drosophila and mammalian tissue culture cells.A high-throughput chemical screen identifies novel inhibitors and enhancers of anti-inflammatory functions of the glucocorticoid receptor.Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation.Ulrike Eggert: big things from small molecules. Interview by Caitlin Sedwick.In vitro imaging of primary neural cell culture from Drosophila.RNA Interference (RNAi) Screening in Drosophila.An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration.

P2860

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P2860

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

http://www.wikidata.org/entity/Q30494581

description

2010 nî lūn-bûn

@nan

2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

@ast

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

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type

label

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

@ast

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

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prefLabel

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

@ast

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

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P1433

Nature Chemical Biology

P1476

Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis.

@en

P2093

Adam B Castoreno

http://www.w3.org/2001/XMLSchema#string

Angelica D Torres

http://www.w3.org/2001/XMLSchema#string

Martha S Vokes

http://www.w3.org/2001/XMLSchema#string

Thouis R Jones

http://www.w3.org/2001/XMLSchema#string

Yegor Smurnyy

http://www.w3.org/2001/XMLSchema#string

P2860

MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody

Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin.

Dissecting the role of Rho-mediated signaling in contractile ring formation.

Anillin binds nonmuscle myosin II and regulates the contractile ring

Pleiotropic effects of statins

CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Rho-kinase controls cell shape changes during cytokinesis

Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets

Rho kinase's role in myosin recruitment to the equatorial cortex of mitotic Drosophila S2 cells is for myosin regulatory light chain phosphorylation

P2888

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457-463

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scholarly article

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10.1038/NCHEMBIO.363

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6

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6

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Anne E Carpenter

Ulrike S Eggert

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2010-05-02T00:00:00Z

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43535447

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1022772324

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20436488

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2873065

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