Spindly/CCDC99 is required for efficient chromosome congression and mitotic checkpoint regulation - Wikidata - awgldk - TriplyDB

Spindly/CCDC99 is required for efficient chromosome congression and mitotic checkpoint regulation

Spindly/CCDC99 is required for efficient chromosome congression and mitotic checkpoint regulation

http://www.wikidata.org/entity/Q30494847

about

The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis Cep57 is a Mis12-interacting kinetochore protein involved in kinetochore targeting of Mad1-Mad2.Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit Kinetochore-microtubule attachment is sufficient to satisfy the human spindle assembly checkpoint Kinetochores: orchestrating the chromosomal minuet.Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis A novel role of farnesylation in targeting a mitotic checkpoint protein, human Spindly, to kinetochores Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint.Conditional targeting of MAD1 to kinetochores is sufficient to reactivate the spindle assembly checkpoint in metaphase.Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology.Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces.Mutual regulation between the spindle checkpoint and APC/C.Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors.Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore.Mitosis. Microtubule detyrosination guides chromosomes during mitosis RanGTP aids anaphase entry through Ubr5-mediated protein turnover.Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster.Quantitative phosphoproteomics reveals genistein as a modulator of cell cycle and DNA damage response pathways in triple-negative breast cancer cells.Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores.Phospho-regulation pathways during egg activation in Drosophila melanogaster.Proteomics Analysis with a Nano Random Forest Approach Reveals Novel Functional Interactions Regulated by SMC Complexes on Mitotic Chromosomes.Crosstalk between microtubule attachment complexes ensures accurate chromosome segregation.Mechanisms of Chromosome Congression during Mitosis.Monitoring the fidelity of mitotic chromosome segregation by the spindle assembly checkpoint.Spindle assembly checkpoint: the third decade.Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint.Dynamic regulation of kinetochore-microtubule interaction during mitosis.Function and regulation of dynein in mitotic chromosome segregation.Chromosome misalignments induce spindle-positioning defects.Structure of the RZZ complex and molecular basis of its interaction with Spindly.Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly.A Molecular View of Kinetochore Assembly and Function.The translational landscape of the splicing factor SRSF1 and its role in mitosis.Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation.Release of Mps1 from kinetochores is crucial for timely anaphase onset.Lipids beyond membranes; farnesylation targets Spindly to kinetochores Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing.PARP inhibition causes premature loss of cohesion in cancer cells.

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Spindly/CCDC99 is required for efficient chromosome congression and mitotic checkpoint regulation

http://www.wikidata.org/entity/Q30494847

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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name

Spindly/CCDC99 is required for ...... mitotic checkpoint regulation

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Spindly/CCDC99 is required for ...... mitotic checkpoint regulation

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type

label

Spindly/CCDC99 is required for ...... mitotic checkpoint regulation

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Spindly/CCDC99 is required for ...... mitotic checkpoint regulation

@en

prefLabel

Spindly/CCDC99 is required for ...... mitotic checkpoint regulation

@ast

Spindly/CCDC99 is required for ...... mitotic checkpoint regulation

@en

P1433

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MBC.E09-04-0356

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Molecular Biology of the Cell

P1476

Spindly/CCDC99 is required for ...... mitotic checkpoint regulation

@en

P2093

Bénédicte Sohm

http://www.w3.org/2001/XMLSchema#string

Cornelia Wandke

http://www.w3.org/2001/XMLSchema#string

Günther Bonn

http://www.w3.org/2001/XMLSchema#string

Michael Hess

http://www.w3.org/2001/XMLSchema#string

Petra Mikolcevic

http://www.w3.org/2001/XMLSchema#string

Stephan Geley

http://www.w3.org/2001/XMLSchema#string

Thomas Ringer

http://www.w3.org/2001/XMLSchema#string

Veronika Rauch

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P2860

Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells

A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function

Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores

Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function

Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase

ZW10 links mitotic checkpoint signaling to the structural kinetochore.

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference

Human NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachment

Dynein light intermediate chain 1 is required for progress through the spindle assembly checkpoint.

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly

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1968-1981

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scholarly article

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10.1091/MBC.E09-04-0356

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12

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21

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P577

2010-04-28T00:00:00Z

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20427577

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2883941

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