TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo - Wikidata - awgldk - TriplyDB

TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo

TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo

http://www.wikidata.org/entity/Q30495308

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Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system Species-specific temperature sensitivity of TRPA1 TRP ion channels in thermosensation, thermoregulation and metabolism TRPA1 as a drug target--promise and challenges The functional and anatomical dissection of somatosensory subpopulations using mouse genetics Cold hypersensitivity increases with age in mice with sickle cell disease Upregulation of the transient receptor potential ankyrin 1 ion channel in the inflamed human and mouse colon and its protective roles Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice TRPA1 contributes to cold hypersensitivity Molecular mechanisms of temperature adaptation Role of TRPA1 in Acute Cardiopulmonary Toxicity of Inhaled Acrolein Ion channel profile of TRPM8 cold receptors reveals a role of TASK-3 potassium channels in thermosensation.Acrolein involvement in sensory and behavioral hypersensitivity following spinal cord injury in the rat Cutaneous TRPM8-expressing sensory afferents are a small population of neurons with unique firing properties.Role of TRPM8 in dorsal root ganglion in nerve injury-induced chronic pain.An approach to identify microRNAs involved in neuropathic pain following a peripheral nerve injury.Labeled lines meet and talk: population coding of somatic sensations.Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling.A novel behavioral assay for measuring cold sensation in mice.A dynamic set point for thermal adaptation requires phospholipase C-mediated regulation of TRPM8 in vivo Plant derived aporphinic alkaloid S-(+)-dicentrine induces antinociceptive effect in both acute and chronic inflammatory pain models: evidence for a role of TRPA1 channels Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons.Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: a comparison with topical menthol.Ionic mechanisms of spinal neuronal cold hypersensitivity in ciguatera.Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception.TRPV1-lineage neurons are required for thermal sensation.Enhanced behavioral responses to cold stimuli following CGRPα sensory neuron ablation are dependent on TRPM8.Scraping through the ice: uncovering the role of TRPM8 in cold transduction The effects of a co-application of menthol and capsaicin on nociceptive behaviors of the rat on the operant orofacial pain assessment device Central connectivity of transient receptor potential melastatin 8-expressing axons in the brain stem and spinal dorsal horn AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia How does morphology relate to function in sensory arbors?Perineural pretreatment of bee venom attenuated the development of allodynia in the spinal nerve ligation injured neuropathic pain model; an experimental study A simple and inexpensive method for determining cold sensitivity and adaptation in mice.Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli.Regulation of TRPM8 channel activity The molecular and cellular basis of thermosensation in mammals.Oxaliplatin-induced neurotoxicity involves TRPM8 in the mechanism of acute hypersensitivity to cold sensation The preventive effect of resiniferatoxin on the development of cold hypersensitivity induced by spinal nerve ligation: involvement of TRPM8 Thermosensitive transient receptor potential (TRP) channel agonists and their role in mechanical, thermal and nociceptive sensations as assessed using animal models.

P2860

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P2860

TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo

http://www.wikidata.org/entity/Q30495308

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

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name

TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo

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TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo

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type

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TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo

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TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo

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TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo

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TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo

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J.PAIN.2010.05.021

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P1476

TRPM8, but not TRPA1, is requi ...... ures and cold-mimetics in vivo

@en

P2093

Amber Bifolck-Fisher

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David D McKemy

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Diana M Bautista

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Wendy M Knowlton

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P2860

Mice left out in the cold: commentary on the phenotype of TRPM8-nulls

How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation.

Pungent products from garlic activate the sensory ion channel TRPA1

TRP channel activation by reversible covalent modification

Detection of cold pain, cold allodynia and cold hyperalgesia in freely behaving rats

Molecular mechanisms of nociception

TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction

TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents

The menthol receptor TRPM8 is the principal detector of environmental cold

TRPM8 is required for cold sensation in mice

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340-350

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10.1016/J.PAIN.2010.05.021

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2

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150

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2010-06-12T00:00:00Z

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44667752

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