ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice.
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Impact of apolipoprotein E on Alzheimer's diseaseApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse modelsThe liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein EACAT1/SOAT1 as a therapeutic target for Alzheimer's diseaseApolipoprotein E and Alzheimer disease: risk, mechanisms and therapyDefensive effect of lansoprazole in dementia of AD type in mice exposed to streptozotocin and cholesterol enriched dietIdentification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in AstrocytesAllopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's diseaseRole of Abca7 in mouse behaviours relevant to neurodegenerative diseases.Genomic convergence and network analysis approach to identify candidate genes in Alzheimer's disease.Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.Frontiers in therapeutic development of allopregnanolone for Alzheimer's disease and other neurological disorders.In vivo and in vitro effects of an apolipoprotein e mimetic peptide on amyloid-β pathologyCholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology.Dab2 attenuates brain injury in APP/PS1 mice via targeting transforming growth factor-beta/SMAD signaling.Nuclear receptors in neurodegenerative diseases.HDL and cognition in neurodegenerative disorders.Cholesterol in brain disease: sometimes determinant and frequently implicated.Effects of NR1H3 genetic variation on the expression of liver X receptor α and the progression of Alzheimer's diseaseUp-regulation of the ATP-binding cassette transporter A1 inhibits hepatitis C virus infection.Improvement of memory deficits and amyloid-β clearance in aged APP23 mice treated with a combination of anti-amyloid-β antibody and LXR agonistNuclear receptors as therapeutic targets for Alzheimer's diseaseOpposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement miceGenomics of Dementia: APOE- and CYP2D6-Related Pharmacogenetics.Role of Liver X Receptor in AD Pathophysiology.Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease.Bexarotene-Activated Retinoid X Receptors Regulate Neuronal Differentiation and Dendritic Complexity.ABC Transporters and the Alzheimer's Disease Enigma.Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 MiceApolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortexReducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice.Mechanisms underlying the rapid peroxisome proliferator-activated receptor-γ-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease.Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient miceRole of liver X receptors in cholesterol efflux and inflammatory signaling (review)Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer's disease.Abca1 deficiency affects Alzheimer's disease-like phenotype in human ApoE4 but not in ApoE3-targeted replacement mice.Regulation of cerebral cholesterol metabolism in Alzheimer disease.Response to comments on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models"Hormonal modulators of glial ABCA1 and apoE levelsSUMO and Alzheimer's disease.
P2860
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P2860
ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
ATP-binding cassette transport ...... sor protein/presenilin 1 mice.
@ast
ATP-binding cassette transport ...... sor protein/presenilin 1 mice.
@en
type
label
ATP-binding cassette transport ...... sor protein/presenilin 1 mice.
@ast
ATP-binding cassette transport ...... sor protein/presenilin 1 mice.
@en
prefLabel
ATP-binding cassette transport ...... sor protein/presenilin 1 mice.
@ast
ATP-binding cassette transport ...... sor protein/presenilin 1 mice.
@en
P2093
P2860
P50
P356
P1476
ATP-binding cassette transport ...... sor protein/presenilin 1 mice.
@en
P2093
Anna Wilkinson
Cheryl L Wellington
James J Donkin
Jeniffer Chan
Jianjia Fan
Jon Collins
Veronica Hirsch-Reinshagen
P2860
P304
34144-34154
P356
10.1074/JBC.M110.108100
P407
P577
2010-08-25T00:00:00Z