Infusion of mature megakaryocytes into mice yields functional platelets. - Wikidata - awgldk - TriplyDB

Infusion of mature megakaryocytes into mice yields functional platelets.

Infusion of mature megakaryocytes into mice yields functional platelets.

http://www.wikidata.org/entity/Q30497158

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Platelet generation in vivo and in vitro Understanding platelet generation from megakaryocytes: implications for in vitro-derived platelets Terminal platelet production is regulated by von Willebrand factor Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1 Identification of a potent small molecule capable of regulating polyploidization, megakaryocyte maturation, and platelet production Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes.Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells.Are there more tricks in the bag for treating thrombocytopenia?Does size matter in platelet production?Crosstalk between Platelets and the Immune System: Old Systems with New Discoveries RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation Steady increment of immature platelet fraction is suppressed by irradiation in single-donor platelet components during storage.Interpreting the developmental dance of the megakaryocyte: a review of the cellular and molecular processes mediating platelet formation.Manipulating megakaryocytes to manufacture platelets ex vivo.Generation of HLA-universal iPSCs-derived megakaryocytes and platelets for survival under refractoriness conditions.Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond.Rapamycin and bafilomycin A1 alter autophagy and megakaryopoiesis.The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors.FLI1 level during megakaryopoiesis affects thrombopoiesis and platelet biology.Towards the Manufacture of Megakaryocytes and Platelets for Clinical Application.Platelet bioreactor-on-a-chip.Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells.OP9 bone marrow stroma cells differentiate into megakaryocytes and platelets.Road blocks in making platelets for transfusion Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells.Humanizing thrombi in mice.Three-dimensional system for the in vitro study of megakaryocytes and functional platelet production using silk-based vascular tubes Comparative analysis of human ex vivo-generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale.The disulfide isomerase ERp57 mediates platelet aggregation, hemostasis, and thrombosis Embryonic stem cells as sources of donor-independent platelets.Alternative blood products and clinical needs in transfusion medicine Platelets in hemostasis and thrombosis: Novel mechanisms of fibrinogen-independent platelet aggregation and fibronectin-mediated protein wave of hemostasis.Identifying and enriching platelet-producing human stem cell-derived megakaryocytes using factor V uptake.Induction of functional platelets from mouse and human fibroblasts by p45NF-E2/Maf Platelets in lung biology.Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration Challenges and promises for the development of donor-independent platelet transfusions.Ex vivo production of platelets from stem cells.Platelet-delivered therapeutics.Threading an elephant through the eye of a needle: Where are platelets made?

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P2860

Infusion of mature megakaryocytes into mice yields functional platelets.

http://www.wikidata.org/entity/Q30497158

description

2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

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name

Infusion of mature megakaryocytes into mice yields functional platelets.

@ast

Infusion of mature megakaryocytes into mice yields functional platelets.

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type

label

Infusion of mature megakaryocytes into mice yields functional platelets.

@ast

Infusion of mature megakaryocytes into mice yields functional platelets.

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prefLabel

Infusion of mature megakaryocytes into mice yields functional platelets.

@ast

Infusion of mature megakaryocytes into mice yields functional platelets.

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P1433

Journal of Clinical Investigation

P1476

Infusion of mature megakaryocytes into mice yields functional platelets.

@en

P2093

Cheng Wang

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G Scott Worthen

http://www.w3.org/2001/XMLSchema#string

Jessica Hirsch

http://www.w3.org/2001/XMLSchema#string

Lubica Rauova

http://www.w3.org/2001/XMLSchema#string

Mortimer Poncz

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Rudy Fuentes

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Yuhuan Wang

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P2860

Localization of distal regulatory domains in the megakaryocyte-specific platelet basic protein/platelet factor 4 gene locus

Analysis of the spatial and temporal characteristics of platelet-delivered factor VIII-based clots

Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells

Metalloproteinase inhibitors improve the recovery and hemostatic function of in vitro-aged or -injured mouse platelets.

Megakaryocyte proliferation and ploidy regulated by the cytoplasmic tail of glycoprotein Ibalpha.

Pathogenesis of thrombocytopenia in cyanotic congenital heart disease.

Platelet count in normal, small, and anemic fetuses.

Characterization of the hematopoietic transcription factor NF-E2 in primary murine megakaryocytes.

Platelets generated in vitro from proplatelet-displaying human megakaryocytes are functional.

Early block to erythromegakaryocytic development conferred by loss of transcription factor GATA-1.

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3917-3922

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10.1172/JCI43326

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11

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2010-10-25T00:00:00Z

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20972336

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2964983

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