Challenges and promises for the development of donor-independent platelet transfusions.
about
Platelet generation in vivo and in vitroUnderstanding platelet generation from megakaryocytes: implications for in vitro-derived plateletsMegakaryocyte- and megakaryocyte precursor-related gene therapiesInducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells.In vitro characterization of SynthoPlate™ (synthetic platelet) technology and its in vivo evaluation in severely thrombocytopenic mice.Arachidonic acid and Docosahexanoic acid enhance platelet formation from human apheresis-derived CD34+ cells.Platelet bioreactor-on-a-chip.Transcriptional diversity during lineage commitment of human blood progenitors.Road blocks in making platelets for transfusionProgrammable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies.SCL/TAL1-mediated transcriptional network enhances megakaryocytic specification of human embryonic stem cells.Comparative analysis of human ex vivo-generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale.Embryonic stem cells as sources of donor-independent platelets.2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium.Microfluidic assessment of functional culture-derived platelets in human thrombi under flow.Identifying and enriching platelet-producing human stem cell-derived megakaryocytes using factor V uptake.Megakaryocytic Maturation in Response to Shear Flow Is Mediated by the Activator Protein 1 (AP-1) Transcription Factor via Mitogen-activated Protein Kinase (MAPK) Mechanotransduction.MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells.Ex vivo production of platelets from stem cells.Genetic engineering of platelets to neutralize circulating tumor cellsBio-inspired nanomedicine strategies for artificial blood components.Human thrombopoiesis depends on Protein kinase Cδ/protein kinase Cε functional couple.Bioenergetic profiling of platelet mitochondria during storage: 4°C storage extends platelet mitochondrial function and viability.Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets.Dissecting the metabolic pathways controlling platelet survival in vivo: are our platelets what they eat?Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice.A uniform-shear rate microfluidic bioreactor for real-time study of proplatelet formation and rapidly-released platelets.Biomaterials and Advanced Technologies for Hemostatic Management of Bleeding.Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve 'golden hour' survival in a porcine model of traumatic arterial hemorrhage.Intravenous administration of synthetic platelets (SynthoPlateTM) in a mouse liver injury model of uncontrolled hemorrhage improves hemostasis.Role of p53 and transcription-independent p53-induced apoptosis in shear-stimulated megakaryocytic maturation, particle generation, and platelet biogenesis
P2860
Q26743455-2300DB96-A747-47C9-9B4B-AB4069882944Q26770860-ABD40199-889C-4B18-87CD-308E2B46F4EBQ26770867-508070C9-E6C7-44C7-ADBC-8F19EAFBE46EQ30657328-E3D7D3C0-C6AD-411C-BA1A-6DA645BE4AD4Q33437439-C2B88695-1590-4347-8671-8805A8C3B0E1Q33440774-0E7B8424-B108-4402-B775-DC17A780B94EQ34209300-3C7ADBED-64AC-4E2C-B18A-CAF360942856Q34626417-E9849DD5-EE87-4AB6-B622-78CF2E00A232Q34671302-6EE5F1BF-5D43-45BD-9793-13F6C080BFDEQ35252648-97072BCF-6192-4027-B6E1-1B797F22D9C6Q35591443-3A2B4C85-BB9D-4B69-BF9F-43F2A6F04C23Q35692415-453D0246-E4AD-4D92-9957-3F29ADD8F8CDQ35836174-29885089-A41A-4132-9603-13A44D73685AQ36068943-4324128F-D587-44AB-813E-FF4E51619098Q36119331-647C964A-E8A6-4465-A94F-A0622A0DCAB4Q36358673-35E38957-02D4-4B65-900E-570E78A571EEQ36778744-EDDEB3C3-4229-4DD5-B826-743FAA03F1F4Q37710268-8370A7D5-6FDA-4169-AE7B-1363C8A610DAQ38187494-21734DBA-5D67-4D4A-9204-1CF46B5E044FQ38790593-D5494A23-6242-4749-BF1E-378E90EFD5BFQ39179984-10A3F305-CE43-4E4C-A294-A01B52891FEDQ39849058-7F45D388-6DDC-474C-83AD-EAE7829B2388Q39899975-6F139D6A-4119-471D-B256-D551967CD5CAQ41107641-DF71BD1F-81C9-4DD6-B170-D107869C77F7Q41196414-C3974E0F-FEF1-4427-8C79-0A919735B53CQ41457201-A0606BC7-D561-4833-B5DE-F6D504E4AF79Q47257067-1B947644-DB43-4CE1-B6C1-1BA5674C97E6Q47324534-DC040883-6516-4AA2-9CEB-03467221D010Q49958847-4A953A26-6BE2-4B48-B031-8819F8B6389AQ51740307-13CAB147-E0D6-4BA3-B86A-CD47188A9372Q58720234-F66B5102-D25D-4904-9EAB-EB68242466CE
P2860
Challenges and promises for the development of donor-independent platelet transfusions.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Challenges and promises for the development of donor-independent platelet transfusions.
@en
type
label
Challenges and promises for the development of donor-independent platelet transfusions.
@en
prefLabel
Challenges and promises for the development of donor-independent platelet transfusions.
@en
P2093
P2860
P1433
P1476
Challenges and promises for the development of donor-independent platelet transfusions.
@en
P2093
Deborah L French
Michele P Lambert
Mortimer Poncz
Rudy Fuentes
Spencer K Sullivan
P2860
P304
P356
10.1182/BLOOD-2012-09-455428
P407
P577
2013-01-15T00:00:00Z