M062 is a host range factor essential for myxoma virus pathogenesis and functions as an antagonist of host SAMD9 in human cells
about
Stress Beyond Translation: Poxviruses and MoreA survey of host range genes in poxvirus genomesPoxviruses and the evolution of host range and virulenceEvolution and divergence of the mammalian SAMD9/SAMD9L gene familyA novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in mice.SAMD9L inactivation promotes cell proliferation via facilitating G1-S transition in hepatitis B virus-associated hepatocellular carcinoma.C7L family of poxvirus host range genes inhibits antiviral activities induced by type I interferons and interferon regulatory factor 1.Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9 to promote expanded host tropism and viral replicationMyxoma virus and the Leporipoxviruses: an evolutionary paradigm.Identification of Restriction Factors by Human Genome-Wide RNA Interference Screening of Viral Host Range Mutants Exemplified by Discovery of SAMD9 and WDR6 as Inhibitors of the Vaccinia Virus K1L-C7L- Mutant.Sterile α Motif Domain Containing 9 Is a Novel Cellular Interacting Partner to Low-Risk Type Human Papillomavirus E6 Proteins.Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins.The poxvirus C7L host range factor superfamily.The N-terminus of vaccinia virus host range protein C7L is essential for function.The current status and future directions of myxoma virus, a master in immune evasion.An interaction domain in human SAMD9 is essential for myxoma virus host-range determinant M062 antagonism of host anti-viral function.Myxoma virus M064 is a novel member of the poxvirus C7L superfamily of host range factors that controls the kinetics of myxomatosis in European rabbits.Myxoma Virus Optimizes Cisplatin for the Treatment of Ovarian Cancer In Vitro and in a Syngeneic Murine Dissemination Model.Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms.SAMD9 is an innate antiviral host factor with stress response properties that can be antagonized by poxviruses.Recombinant myxoma virus lacking all poxvirus ankyrin-repeat proteins stimulates multiple cellular anti-viral pathways and exhibits a severe decrease in virulenceA paralogous pair of mammalian host restriction factors form a critical host barrier against poxvirus infection.Constitutional SAMD9L mutations cause familial myelodysplastic syndrome and transient monosomy 7.
P2860
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P2860
M062 is a host range factor essential for myxoma virus pathogenesis and functions as an antagonist of host SAMD9 in human cells
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
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2011年論文
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2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
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2011年论文
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name
M062 is a host range factor es ...... t of host SAMD9 in human cells
@ast
M062 is a host range factor es ...... t of host SAMD9 in human cells
@en
type
label
M062 is a host range factor es ...... t of host SAMD9 in human cells
@ast
M062 is a host range factor es ...... t of host SAMD9 in human cells
@en
prefLabel
M062 is a host range factor es ...... t of host SAMD9 in human cells
@ast
M062 is a host range factor es ...... t of host SAMD9 in human cells
@en
P2093
P2860
P356
P1433
P1476
M062 is a host range factor es ...... t of host SAMD9 in human cells
@en
P2093
Leiliang Zhang
Sonia Wennier
P2860
P304
P356
10.1128/JVI.02243-10
P577
2011-01-19T00:00:00Z